MEMPHIS TN 381032893
Tel: (901) 287-4495


  • PostDoc, UTHSC, Immunology
  • Ph.D., Seoul National University, Immunology
  • M.S., Kangwon National University, Oncology
  • B.S., Kangwon National University, Biology

Curriculum Vitae

Research Keywords

 Infectious Diease, respiratory syncytial virus (RSV), cell mediated immune responses, mathematical modeling in RSV infection

Research Interest/Specialty

 Using cellular biology and immunology to investigate RSV infection in children and adults.

Curriculum Vitae


  1. Kim, YI, DeVincenzo, JP, Jones, BG, Rudraraju, R, Harrison, L, Meyers, R, Cehelsky, J, Alvarez, R, Hurwitz, JL. Respiratory syncytial virus human experimental infection model: provenance, production, and sequence of low-passaged memphis-37 challenge virus. PLoS One, 9 (11), e113100, 2014.
  2. Cormier, SA, Shrestha, B, Saravia, J, Lee, GI, Shen, L, DeVincenzo, JP, Kim, YI, You, D. Limited type I interferons and plasmacytoid dendritic cells during neonatal respiratory syncytial virus infection permit immunopathogenesis upon reinfection. J Virol, 88 (16), 9350-60, 2014.
  3. Kim, YI, Park, JE, Kwon, KH, Hong, CY, Yi, AK. Interleukin-1 receptor-associated kinase 2- and protein kinase D1-dependent regulation of IRAK-monocyte expression by CpG DNA. PLoS One, 7 (8), e43970, 2011.
  4. Kim, YI, Park, JE, Brand, DD, Fitzpatrick, EA, Yi, AK. Protein kinase D1 is essential for the proinflammatory response induced by hypersensitivity pneumonitis-causing thermophilic actinomycetes Saccharopolyspora rectivirgula. J Immunol, 184 (6), 3145-56, 2010.
  5. Park, JE, Kim, YI, Yi, AK. Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway. J Immunol, 182 (10), 6316-27, 2009.
  6. Park, JE, Kim, YI, Yi, AK. Protein kinase D1: a new component in TLR9 signaling. J Immunol, 181 (3), 2044-55, 2008.
  7. Kim, YI, Park, JE, Martinez-Hernandez, A, Yi, AK. CpG DNA prevents liver injury and shock-mediated death by modulating expression of interleukin-1 receptor-associated kinases. J Biol Chem, 283 (22), 15258-70, 2008.
  8. Hahm, E, Jin, DH, Kang, JS, Kim, YI, Hong, SW, Lee, SK, Kim, HN, Jung, da J, Kim, JE, Shin, DH, Hwang, YI, Kim, YS, Hur, DY, Yang, Y, Cho, D, Lee, MS, Lee, WJ. The molecular mechanisms of vitamin C on cell cycle regulation in B16F10 murine melanoma. J Cell Biochem, 102 (4), 1002-10, 2007.
  9. Talati, AJ, Kim, HJ, Kim, YI, Yi, AK, English, BK. Role of bacterial DNA in macrophage activation by group B streptococci. Microbes Infect, 10 (10-11), 1106-13, 2007.
  10. Kim, YS, Park, GB, Choi, YM, Kwon, OS, Song, HK, Kang, JS, Kim, YI, Lee, WJ, Hur, DY. Ligation of centrocyte/centroblast marker 1 on Epstein-Barr virus--transformed B lymphocytes induces cell death in a reactive oxygen species--dependent manner. Hum Immunol, 67 (10), 795-807, 2006.
  11. Kang, JS, Cho, D, Kim, YI, Hahm, E, Kim, YS, Jin, SN, Kim, HN, Kim, D, Hur, D, Park, H, Hwang, YI, Lee, WJ. Sodium ascorbate (vitamin C) induces apoptosis in melanoma cells via the down-regulation of transferrin receptor dependent iron uptake. J Cell Physiol, 204 (1), 192-7, 2005.
  12. Yang, Y, Hahm, E, Kim, Y, Kang, J, Lee, W, Han, I, Myung, P, Kang, H, Park, H, Cho, D. Regulation of IL-18 expression by CRH in mouse microglial cells. Immunol Lett, 98 (2), 291-6, 2005.
  13. Cho, D, Kim, YI, Kang, JS, Hahm, E, Yang, Y, Kim, D, Kim, S, Kim, YS, Hur, D, Park, H, Hwang, YI, Kim, TS, Lee, WJ. Resistance to cytotoxic chemotherapy is induced by NK cells in non-Hodgkin's Lymphoma Cells. J Clin Immunol, 24 (5), 553-60, 2004.
  14. Cho, D, Hahm, E, Kang, JS, Kim, YI, Yang, Y, Park, JH, Kim, D, Kim, S, Kim, YS, Hur, D, Park, H, Pang, S, Hwang, YI, Lee, WJ. Vitamin C downregulates interleukin-18 production by increasing reactive oxygen intermediate and mitogen-activated protein kinase signalling in B16F10 murine melanoma cells. Melanoma Res, 13 (6), 549-54, 2003.
  15. Kang, JS, Cho, D, Kim, YI, Hahm, E, Yang, Y, Kim, D, Hur, D, Park, H, Bang, S, Hwang, YI, Lee, WJ. L-ascorbic acid (vitamin C) induces the apoptosis of B16 murine melanoma cells via a caspase-8-independent pathway. Cancer Immunol Immunother, 52 (11), 693-8, 2003.
  16. Kim, YI, Park, S, Jeoung, DI, Lee, H. Point mutations affecting the oligomeric structure of Nm23-H1 abrogates its inhibitory activity on colonization and invasion of prostate cancer cells. Biochem Biophys Res Commun, 307 (2), 281-9, 2003.
  17. Cho, D, Seung Kang, J, Hoon Park, J, Kim, YI, Hahm, E, Lee, J, Yang, Y, Jeon, J, Song, H, Park, H, Kim, T, Pang, S, Kim, CW, Il Hwang, Y, Jae Lee, W. The enhanced IL-18 production by UVB irradiation requires ROI and AP-1 signaling in human keratinocyte cell line (HaCaT). Biochem Biophys Res Commun, 298 (2), 289-95, 2002.
  18. Kim, D, Hur, DY, Kim, YS, Lee, K, Lee, Y, Cho, D, Kang, JS, Kim, YI, Hahm, E, Yang, Y, Yoon, S, Kim, S, Lee, WB, Park, HY, Kim, YB, Hwang, YI, Chang, KY, Lee, WJ. CM1 ligation initiates apoptosis in a caspase 8-dependent manner in Ramos cells and in a mitochondria-controlled manner in Raji cells. Hum Immunol, 63 (7), 576-87, 2002.
  19. Park, H, Byun, D, Kim, TS, Kim, YI, Kang, JS, Hahm, ES, Kim, SH, Lee, WJ, Song, HK, Yoon, DY, Kang, CJ, Lee, C, Houh, D, Kim, H, Cho, B, Kim, Y, Yang, YH, Min, KH, Cho, DH. Enhanced IL-18 expression in common skin tumors. Immunol Lett, 79 (3), 215-9, 2001.
  20. Hur, DY, Kim, S, Kim, YI, Min, HY, Kim, DJ, Lee, DS, Cho, D, Hwang, YI, Hwang, DH, Park, SH, Ahn, HK, Chang, KY, Kim, YB, Lee, WJ. CM1, a possible novel activation molecule on human lymphocytes. Immunol Lett, 74 (2), 95-102, 2000.