Assistant Professor
Nursing-Academic Programs
Assistant Professor
Preventive Medicine

Office: 504 920 MADISON BUILDING
MEMPHIS TN 381632275
Tel: (901) 448-2139


  • Ph.D., University of Memphis, Memphis, TN, Applied Statistics
  • M.S., Iowa State University, Ames, IA, Statistics
  • Ph.D., Iowa State University, Ames, IA, Molecular, Cellular, and Developmental Biology
  • M.S., Institute of Genetics, Chinese Academy of Science, Beijing, China, Genetics
  • B.A., Shandong Agricultural University, Tai'an, China, Horticulture


  1. Elsayed, AH, Cao, X, Crews, KR, Gandhi, V, Plunkett, W, Rubnitz, JE, Ribeiro, RC, Pounds, SB, Lamba, JK. Comprehensive Ara-C SNP score predicts leukemic cell intracellular ara-CTP levels in pediatric acute myeloid leukemia patients. Pharmacogenomics, 19 (14), 1101-1110, 2018.
  2. Lamba, JK, Cao, X, Raimondi, SC, Rafiee, R, Downing, JR, Shi, L, Gruber, T, Ribeiro, RC, Rubnitz, JE, Pounds, SB. Correction: Integrated epigenetic and genetic analysis identifies markers of prognostic significance in pediatric acute myeloid leukemia. Oncotarget, 9 (54), 30473, 2018.
  3. Howard, SC, Zaidi, A, Cao, X, Weil, O, Bey, P, Patte, C, Samudio, A, Haddad, L, Lam, CG, Moreira, C, Pereira, A, Harif, M, Hessissen, L, Choudhury, S, Fu, L, Caniza, MA, Lecciones, J, Traore, F, Ribeiro, RC, Gagnepain-Lacheteau, A. The My Child Matters programme: effect of public-private partnerships on paediatric cancer care in low-income and middle-income countries. Lancet Oncol, 19 (5), e252-e266, 2018.
  4. Ma, X, Liu, Y, Liu, Y, Alexandrov, LB, Edmonson, MN, Gawad, C, Zhou, X, Li, Y, Rusch, MC, Easton, J, Huether, R, Gonzalez-Pena, V, Wilkinson, MR, Hermida, LC, Davis, S, Sioson, E, Pounds, S, Cao, X, Ries, RE, Wang, Z, Chen, X, Dong, L, Diskin, SJ, Smith, MA, Guidry Auvil, JM, Meltzer, PS, Lau, CC, Perlman, EJ, Maris, JM, Meshinchi, S, Hunger, SP, Gerhard, DS, Zhang, J. Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours. Nature, 2018.
  5. Qian, M, Cao, X, Devidas, M, Yang, W, Cheng, C, Dai, Y, Carroll, A, Heerema, NA, Zhang, H, Moriyama, T, Gastier-Foster, JM, Xu, H, Raetz, E, Larsen, E, Winick, N, Bowman, WP, Martin, PL, Mardis, ER, Fulton, R, Zambetti, G, Borowitz, M, Wood, B, Nichols, KE, Carroll, WL, Pui, CH, Mullighan, CG, Evans, WE, Hunger, SP, Relling, MV, Loh, ML, Yang, JJ. TP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children. J Clin Oncol, JCO2017755215, 2018.
  6. Inaba, H, Cao, X, Han, AQ, Panetta, JC, Ness, KK, Metzger, ML, Rubnitz, JE, Ribeiro, RC, Sandlund, JT, Jeha, S, Cheng, C, Pui, CH, Relling, MV, Kaste, SC. Bone mineral density in children with acute lymphoblastic leukemia. Cancer, 2017.
  7. Ramsey, LB, Pounds, S, Cheng, C, Cao, X, Yang, W, Smith, C, Karol, SE, Liu, C, Panetta, JC, Inaba, H, Rubnitz, JE, Metzger, ML, Ribeiro, RC, Sandlund, JT, Jeha, S, Pui, CH, Evans, WE, Relling, MV. Genetics of pleiotropic effects of dexamethasone. Pharmacogenet Genomics, 27 (8), 294-302, 2017.
  8. Karol, SE, Larsen, E, Cheng, C, Cao, X, Yang, W, Ramsey, LB, Fernandez, CA, McCorkle, JR, Paugh, SW, Autry, RJ, Lopez-Lopez, E, Diouf, B, Jeha, S, Pui, CH, Raetz, EA, Winick, NJ, Carroll, WL, Hunger, SP, Loh, ML, Devidas, M, Evans, WE, Yang, JJ, Relling, MV. Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia. Leukemia, 31 (6), 1325-1332, 2017.
  9. Cao, X, Crews, KR, Downing, J, Lamba, J, Pounds, SB. CC-PROMISE effectively integrates two forms of molecular data with multiple biologically related endpoints. BMC Bioinformatics, 17 (Suppl 13), 382, 2016.
  10. Nguyen, R, Jeha, S, Zhou, Y, Cao, X, Cheng, C, Bhojwani, D, Campbell, P, Howard, SC, Rubnitz, J, Ribeiro, RC, Sandlund, JT, Gruber, T, Inaba, H, Pui, CH, Metzger, ML. The Role of Leukapheresis in the Current Management of Hyperleukocytosis in Newly Diagnosed Childhood Acute Lymphoblastic Leukemia. Pediatr Blood Cancer, 63 (9), 1546-51, 2016.
  11. Faber, ZJ, Chen, X, Gedman, AL, Boggs, K, Cheng, J, Ma, J, Radtke, I, Chao, JR, Walsh, MP, Song, G, Andersson, AK, Dang, J, Dong, L, Liu, Y, Huether, R, Cai, Z, Mulder, H, Wu, G, Edmonson, M, Rusch, M, Qu, C, Li, Y, Vadodaria, B, Wang, J, Hedlund, E, Cao, X,...,Zhang J, Klco JM, Downing JR. The genomic landscape of core-binding factor acute myeloid leukemias. Nat Genet, .48 (12), 1551-1556, 2016.
  12. Moriyama, T, Metzger, ML, Wu, G, Nishii, R, Qian, M, Devidas, M, Yang, W, Cheng, C, Cao, X, Quinn, E, Raimondi, S, Gastier-Foster, JM, Raetz, E, Larsen, E, Martin, PL, Bowman, WP, Winick, N, Komada, Y, Wang, S, Edmonson, M, Xu, H, Mardis, E, Fulton, R, Pui, CH, Mullighan, C, Evans, WE, Zhang, J, Hunger, SP, Relling, MV, Nichols, KE, Loh, ML, Yang, JJ. Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study. Lancet Oncol, 16 (16), 1659-66, 2015.
  13. Bhise, NS, Chauhan, L, Shin, M, Cao, X, Pounds, S, Lamba, V, Lamba, JK. MicroRNA-mRNA Pairs Associated with Outcome in AML: From In Vitro Cell-Based Studies to AML Patients. Front Pharmacol, 6, 324, 2015.
  14. Lamba, JK, Pounds, S, Cao, X, Crews, KR, Cogle, CR, Bhise, N, Raimondi, SC, Downing, JR, Baker, SD, Ribeiro, RC, Rubnitz, JE. Clinical significance of in vivo cytarabine-induced gene expression signature in AML. Leuk Lymphoma, 57 (4), 909-20, 2015.
  15. Karol, SE, Coustan-Smith, E, Cao, X, Shurtleff, SA, Raimondi, SC, Choi, JK, Ribeiro, RC, Dahl, GV, Bowman, WP, Taub, JW, Degar, B, Leung, W, Downing, JR, Pui, CH, Rubnitz, JE, Campana, D, Inaba, H. Prognostic factors in children with acute myeloid leukaemia and excellent response to remission induction therapy. Br J Haematol, 168 (1), 94-101, 2015.
  16. Burke, MJ, Lamba, JK, Pounds, S, Cao, X, Ghodke-Puranik, Y, Lindgren, BR, Weigel, BJ, Verneris, MR, Miller, JS. A therapeutic trial of decitabine and vorinostat in combination with chemotherapy for relapsed/refractory acute lymphoblastic leukemia. Am J Hematol, 89 (9), 889-95, 2014.
  17. Rubnitz, JE, Inaba, H, Leung, WH, Pounds, S, Cao, X, Campana, D, Ribeiro, RC, Pui, CH. Definition of cure in childhood acute myeloid leukemia. Cancer, 120 (16), 2490-6, 2014.
  18. Inaba, H, Gaur, AH, Cao, X, Flynn, PM, Pounds, SB, Avutu, V, Marszal, LN, Howard, SC, Pui, CH, Ribeiro, RC, Hayden, RT, Rubnitz, JE. Feasibility, efficacy, and adverse effects of outpatient antibacterial prophylaxis in children with acute myeloid leukemia. Cancer, 120 (13), 1985-92, 2014.
  19. Cao, X, Mitra, AK, Pounds, S, Crews, KR, Gandhi, V, Plunkett, W, Dolan, ME, Hartford, C, Raimondi, S, Campana, D, Downing, J, Rubnitz, JE, Ribeiro, RC, Lamba, JK. RRM1 and RRM2 pharmacogenetics: association with phenotypes in HapMap cell lines and acute myeloid leukemia patients. Pharmacogenomics, 14 (12), 1449-66, 2013.
  20. Buaboonnam, J, Cao, X, Pauley, JL, Pui, CH, Ribeiro, RC, Rubnitz, JE, Inaba, H. Sequential administration of methotrexate and asparaginase in relapsed or refractory pediatric acute myeloid leukemia. Pediatr Blood Cancer, 60 (7), 1161-4, 2013.
  21. Gamazon, ER, Lamba, JK, Pounds, S, Stark, AL, Wheeler, HE, Cao, X, Im, HK, Mitra, AK, Rubnitz, JE, Ribeiro, RC, Raimondi, S, Campana, D, Crews, KR, Wong, SS, Welsh, M, Hulur, I, Gorsic, L, Hartford, CM, Zhang, W, Cox, NJ, Dolan, ME. Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients. Blood, 121 (21), 4366-76, 2013.
  22. O'Brien, MM, Cao, X, Pounds, S, Dahl, GV, Raimondi, SC, Lacayo, NJ, Taub, J, Chang, M, Weinstein, HJ, Ravindranath, Y, Inaba, H, Campana, D, Pui, CH, Rubnitz, JE. Prognostic features in acute megakaryoblastic leukemia in children without Down syndrome: a report from the AML02 multicenter trial and the Children's Oncology Group Study POG 9421. Leukemia, 27 (3), 731-4, 2013.
  23. Mortland, L, Alonzo, TA, Walter, RB, Gerbing, RB, Mitra, AK, Pollard, JA, Loken, MR, Hirsch, B, Raimondi, S, Franklin, J, Pounds, S, Cao, X, Rubnitz, JE, Ribeiro, RC, Gamis, A, Meshinchi, S, Lamba, JK. Clinical significance of CD33 nonsynonymous single-nucleotide polymorphisms in pediatric patients with acute myeloid leukemia treated with gemtuzumab-ozogamicin-containing chemotherapy. Clin Cancer Res, 19 (6), 1620-7, 2013.
  24. Rubnitz, JE, Pounds, S, Cao, X, Jenkins, L, Dahl, G, Bowman, WP, Taub, JW, Pui, CH, Ribeiro, RC, Campana, D, Inaba, H. Treatment outcome in older patients with childhood acute myeloid leukemia. Cancer, 118 (24), 6253-9, 2012.
  25. Inaba, H, Surprise, HC, Pounds, S, Cao, X, Howard, SC, Ringwald-Smith, K, Buaboonnam, J, Dahl, G, Bowman, WP, Taub, JW, Campana, D, Pui, CH, Ribeiro, RC, Rubnitz, JE. Effect of body mass index on the outcome of children with acute myeloid leukemia. Cancer, 118 (23), 5989-96, 2012.
  26. Yang, JJ, Cheng, C, Devidas, M, Cao, X, Campana, D, Yang, W, Fan, Y, Neale, G, Cox, N, Scheet, P, Borowitz, MJ, Winick, NJ, Martin, PL, Bowman, WP, Camitta, B, Reaman, GH, Carroll, WL, Willman, CL, Hunger, SP, Evans, WE, Pui, CH, Loh, M, Relling, MV. Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia. Blood, 120 (20), 4197-204, 2012.
  27. Inaba, H, Coustan-Smith, E, Cao, X, Pounds, SB, Shurtleff, SA, Wang, KY, Raimondi, SC, Onciu, M, Jacobsen, J, Ribeiro, RC, Dahl, GV, Bowman, WP, Taub, JW, Degar, B, Leung, W, Downing, JR, Pui, CH, Rubnitz, JE, Campana, D. Comparative analysis of different approaches to measure treatment response in acute myeloid leukemia. J Clin Oncol, 30 (29), 3625-32, 2012.
  28. Mitra, AK, Crews, KR, Pounds, S, Cao, X, Feldberg, T, Ghodke, Y, Gandhi, V, Plunkett, W, Dolan, ME, Hartford, C, Raimondi, S, Campana, D, Downing, J, Rubnitz, JE, Ribeiro, RC, Lamba, JK. Genetic variants in cytosolic 5'-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia. J Pharmacol Exp Ther, 339 (1), 9-23, 2011.
  29. Mitra, AK, Crews, K, Pounds, S, Cao, X, Downing, JR, Raimondi, S, Campana, D, Ribeiro, RC, Rubnitz, JE, Lamba, JK. Impact of genetic variation in FKBP5 on clinical response in pediatric acute myeloid leukemia patients: a pilot study. Leukemia, 25 (8), 1354-6, 2011.
  30. Pounds, S, Cao, X, Cheng, C, Yang, JJ, Campana, D, Pui, CH, Evans, WE, Relling, MV. Integrated analysis of pharmacologic, clinical and SNP microarray data using Projection Onto the Most Interesting Statistical Evidence with Adaptive Permutation Testing. Int J Data Min Bioinform, 5 (2), 143-57, 2011.
  31. Lamba, JK, Crews, KR, Pounds, SB, Cao, X, Gandhi, V, Plunkett, W, Razzouk, BI, Lamba, V, Baker, SD, Raimondi, SC, Campana, D, Pui, CH, Downing, JR, Rubnitz, JE, Ribeiro, RC. Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes. Pharmacogenomics, 12 (3), 327-39, 2011.
  32. Yang, JJ, Cheng, C, Devidas, M, Cao, X, Fan, Y, Campana, D, Yang, W, Neale, G, Cox, NJ, Scheet, P, Borowitz, MJ, Winick, NJ, Martin, PL, Willman, CL, Bowman, WP, Camitta, BM, Carroll, A, Reaman, GH, Carroll, WL, Loh, M, Hunger, SP, Pui, CH, Evans, WE, Relling, MV. Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia. Nat Genet, 43 (3), 237-41, 2011.
  33. Inaba, H, Cao, X, Pounds, S, Pui, CH, Rubnitz, JE, Ribeiro, RC, Razzouk, BI. Randomized trial of 2 dosages of prophylactic granulocyte-colony-stimulating factor after induction chemotherapy in pediatric acute myeloid leukemia. Cancer, 117 (6), 1313-20, 2011.
  34. Rubnitz, JE, Inaba, H, Dahl, G, Ribeiro, RC, Bowman, WP, Taub, J, Pounds, S, Razzouk, BI, Lacayo, NJ, Cao, X, Meshinchi, S, Degar, B, Airewele, G, Raimondi, SC, Onciu, M, Coustan-Smith, E, Downing, JR, Leung, W, Pui, CH, Campana, D. Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML02 multicentre trial. Lancet Oncol, 11 (6), 543-52, 2010.
  35. Pounds, S, Cheng, C, Cao, X, Crews, KR, Plunkett, W, Gandhi, V, Rubnitz, J, Ribeiro, RC, Downing, JR, Lamba, J. PROMISE: a tool to identify genomic features with a specific biologically interesting pattern of associations with multiple endpoint variables. Bioinformatics, 25 (16), 2013-9, 2009.
  36. Radtke, I, Mullighan, CG, Ishii, M, Su, X, Cheng, J, Ma, J, Ganti, R, Cai, Z, Goorha, S, Pounds, SB, Cao, X, Obert, C, Armstrong, J, Zhang, J, Song, G, Ribeiro, RC, Rubnitz, JE, Raimondi, SC, Shurtleff, SA, Downing, JR. Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Proc Natl Acad Sci U S A, 106 (31), 12944-9, 2009.
  37. Hinds, PS, Billups, CA, Cao, X, Gattuso, JS, Burghen, E, West, N, Rubnitz, JE, Daw, NC. Health-related quality of life in adolescents at the time of diagnosis with osteosarcoma or acute myeloid leukemia. Eur J Oncol Nurs, 13 (3), 156-63, 2009.
  38. Rubnitz, JE, Onciu, M, Pounds, S, Shurtleff, S, Cao, X, Raimondi, SC, Behm, FG, Campana, D, Razzouk, BI, Ribeiro, RC, Downing, JR, Pui, CH. Acute mixed lineage leukemia in children: the experience of St Jude Children's Research Hospital. Blood, 113 (21), 5083-9, 2009.
  39. Lamba, JK, Pounds, S, Cao, X, Downing, JR, Campana, D, Ribeiro, RC, Pui, CH, Rubnitz, JE. Coding polymorphisms in CD33 and response to gemtuzumab ozogamicin in pediatric patients with AML: a pilot study. Leukemia, 23 (2), 402-4, 2009.
  40. Yang, JJ, Cheng, C, Yang, W, Pei, D, Cao, X, Fan, Y, Pounds, SB, Neale, G, Treviño, LR, French, D, Campana, D, Downing, JR, Evans, WE, Pui, CH, Devidas, M, Bowman, WP, Camitta, BM, Willman, CL, Davies, SM, Borowitz, MJ, Carroll, WL, Hunger, SP, Relling, MV. Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. JAMA, 301 (4), 393-403, 2009.
  41. Cao, X, Costa, LM, Biderre-Petit, C, Kbhaya, B, Dey, N, Perez, P, McCarty, DR, Gutierrez-Marcos, JF, Becraft, PW. Abscisic acid and stress signals induce Viviparous1 expression in seed and vegetative tissues of maize. Plant Physiol, 143 (2), 720-31, 2007.
  42. Cao, X, Li, K, Suh, SG, Guo, T, Becraft, PW. Molecular analysis of the CRINKLY4 gene family in Arabidopsis thaliana. Planta, 220 (5), 645-57, 2005.
  43. Lü, D, Cao, X, Tang, S, Tian, X. Regeneration of foreign genes co-transformed plants of Medicago sativa L by Agrobacterium rhizogenes. Sci China C Life Sci, 43 (4), 387-94, 2000.