TAYEBEH POURMOTABBED, Ph.D., B.A.

Professor Molecular Sciences
Adjunct Professor Neurosurgery

Office: 401C MOLECULAR SCIENCES BUILDING
858 MADISON AVENUE
MEMPHIS TN 381630000
Tel: (901) 448-4361
tpourmotabbe@uthsc.edu

Publications

  1. Chang, JJ, Stanfill, A, Pourmotabbed, T. The Role of Matrix Metalloproteinase Polymorphisms in Ischemic Stroke. Int J Mol Sci, 17 (8), 2016.
  2. Nomani, H, Hagh-Nazari, L, Aidy, A, Vaisi-Raygani, A, Kiani, A, Rahimi, Z, Bahrehmand, F, Shakiba, E, Mozaffari, HR, Tavilani, H, Pourmotabbed, T. Association between GSTM1, GSTT1, and GSTP1 variants and the risk of end stage renal disease. Ren Fail, 1-7, 2016.
  3. Mohammadi, Y, Vaisi-Raygani, A, Shakiba, E, Bahrehmand, F, Khodarahmi, R, Nemati, H, Rahimi, Z, Kiani, A, Rahimi, Z, Vaisi-Raygani, H, Vaisi-Raygani, H, Pourmotabbed, T. Angiotensin II type 1 receptor A1166 C (rs5186) gene polymorphism increased risk and severity of psoriasis, contribution to oxidative stress, antioxidant statues, lipid peroxidation and correlation with vascular adhesion protein 1, preliminary report. J Eur Acad Dermatol Venereol, 30 (8), 1395-7, 2016.
  4. Haghnazari, L, Vaisi-Raygani, A, Keshvarzi, F, Ferdowsi, F, Goodarzi, M, Rahimi, Z, Baniamerian, H, Tavilani, H, Vaisi-Raygani, H, Vaisi-Raygani, H, Pourmotabbed, T. Effect of Acetylcholinesterase and Butyrylcholinesterase on Intrauterine Insemination, Contribution to Inflammations, Oxidative Stress and Antioxidant Status; A Preliminary Report. J Reprod Infertil, 17 (3), 157-62, 2016.
  5. Bahrehmand, F, Kiani, A, Vaisi-Raygani, A, Bashiri, H, Zobeiri, M, Tanhapour, M, Pourmotabbed, T. Pharmacogenetics of drug metabolizing enzyme: thiopurine methyl transferase phenotypes and multidrug resistance 1 gene polymorphism in inflammatory bowel disease. Cell Mol Biol (Noisy-le-grand), 62 (7), 102-9, 2016.
  6. Shahjouei, S, Ansari, S, Pourmotabbed, T, Zand, R. Potential Roles of Adropin in Central Nervous System: Review of Current Literature. Front Mol Biosci, 3, 25, 2016.
  7. Bahrehmand, F, Vaisi-Raygani, A, Kiani, A, Rahimi, Z, Tavilani, H, Ardalan, M, Vaisi-Raygani, H, Shakiba, E, Pourmotabbed, T. Matrix metalloproteinase 9 polymorphisms and systemic lupus erythematosus: correlation with systemic inflammatory markers and oxidative stress. Lupus, 24 (6), 597-605, 2015.
  8. Pourmotabbed, A, Mahmoodi, G, Mahmoodi, S, Mohammadi-Farani, A, Nedaei, SE, Pourmotabbed, T, Pourmotabbed, T. Effect of central muscarinic receptors on passive-avoidance learning deficits induced by prenatal pentylenetetrazol kindling in male offspring. Neuroscience, 279, 232-7, 2014.
  9. Shakiba, E, Tavilani, H, Goodarzi, MT, Kiani, A, Pourmotabbed, T, Vaisi-Raygani, A. The ITGAV-rs3911238 polymorphism is associated with disease activity in rheumatoid arthritis. Iran J Allergy Asthma Immunol, 13 (5), 356-63, 2014.
  10. Asefi, M, Vaisi-Raygani, A, Khodarahmi, R, Nemati, H, Rahimi, Z, Vaisi-Raygani, H, Tavilani, H, Pourmotabbed, T. Methylentetrahydrofolatereductase (rs1801133) polymorphism and psoriasis: contribution to oxidative stress, lipid peroxidation and correlation with vascular adhesion protein 1, preliminary report. J Eur Acad Dermatol Venereol, 28 (9), 1192-8, 2014.
  11. Bahrehmand, F, Vaisi-Raygani, A, Rahimi, Z, Ahmadi, R, Kiani, A, Tavilani, H, Vaisi-Raygani, H, Pourmotabbed, T. Synergistic effects of BuChE non-UU phenotype and paraoxonase (PON1) 55 M allele on the risk of systemic lupus erythematosus: influence on lipid and lipoprotein metabolism and oxidative stress, preliminary report. Lupus, 23 (3), 263-72, 2014.
  12. Hallett, MA, Dalal, P, Sweatman, TW, Pourmotabbed, T. The distribution, clearance, and safety of an anti-MMP-9 DNAzyme in normal and MMTV-PyMT transgenic mice. Nucleic Acid Ther, 23 (6), 379-88, 2013.
  13. Bahrehmand, F, Vaisi-Raygani, A, Ahmadi, R, Kiani, A, Rahimi, Z, Tavilani, H, Pourmotabbed, T. Paraoxonase (PON1) 55 polymorphism and association with systemic lupus erythematosus. Iran J Allergy Asthma Immunol, 12 (3), 211-9, 2013.
  14. Hallett, MA, Teng, B, Hasegawa, H, Schwab, LP, Seagroves, TN, Pourmotabbed, T. Anti-matrix metalloproteinase-9 DNAzyme decreases tumor growth in the MMTV-PyMT mouse model of breast cancer. Breast Cancer Res, 15 (1), R12, 2013.
  15. Asefi, M, Vaisi-Raygani, A, Bahrehmand, F, Kiani, A, Rahimi, Z, Nomani, H, Ebrahimi, A, Tavilani, H, Pourmotabbed, T. Paraoxonase 1 (PON1) 55 polymorphism, lipid profiles and psoriasis. Br J Dermatol, 167 (6), 1279-86, 2012.
  16. Azimi, L, Pourmotabbed, A, Ghadami, MR, Nedaei, SE, Pourmotabbed, T. Effects of Peripheral and Intra-hippocampal Administration of Sodium Salicylate on Spatial Learning and Memory of Rats. Iran J Basic Med Sci, 15 (2), 709-18, 2012.
  17. Kharrazi, H, Vaisi-Raygani, A, Rahimi, Z, Tavilani, H, Aminian, M, Pourmotabbed, T. Association between enzymatic and non-enzymatic antioxidant defense mechanism with apolipoprotein E genotypes in Alzheimer disease. Clin Biochem, 41 (12), 932-6, 2008.
  18. Vaisi-Raygani, A, Rahimi, Z, Entezami, H, Kharrazi, H, Bahrhemand, F, Tavilani, H, Rezaei, M, Kiani, A, Nomanpour, B, Pourmotabbed, T. Butyrylcholinesterase K variants increase the risk of coronary artery disease in the population of western Iran. Scand J Clin Lab Invest, 68 (2), 123-9, 2007.
  19. Vaisi-Raygani, A, Kharrazi, H, Rahimi, Z, Pourmotabbed, T. Frequencies of apolipoprotein E polymorphism in a healthy Kurdish population from Kermanshah, Iran. Hum Biol, 79 (5), 579-87, 2007.
  20. Vaisi-Raygani, A, Rahimi, Z, Nomani, H, Tavilani, H, Pourmotabbed, T. The presence of apolipoprotein epsilon4 and epsilon2 alleles augments the risk of coronary artery disease in type 2 diabetic patients. Clin Biochem, 40 (15), 1150-6, 2007.
  21. Vaisi-Raygani, A, Rahimi, Z, Kharazi, H, Tavilani, H, Aminiani, M, Kiani, A, Vaisi-Raygani, A, Pourmotabbed, T. Determination of butyrylcholinesterase (BChE) phenotypes to predict the risk of prolonged apnea in persons receiving succinylcholine in the healthy population of western Iran. Clin Biochem, 40 (9-10), 629-33, 2007.
  22. O'Farrell, TJ, Guo, R, Hasegawa, H, Pourmotabbed, T. Matrix metalloproteinase-1 takes advantage of the induced fit mechanism to cleave the triple-helical type I collagen molecule. Biochemistry, 45 (51), 15411-8, 2006.
  23. Raygani, AV, Rahimi, Z, Kharazi, H, Tavilani, H, Pourmotabbed, T. Association between apolipoprotein E polymorphism and serum lipid and apolipoprotein levels with Alzheimer's disease. Neurosci Lett, 408 (1), 68-72, 2006.
  24. Kharrazi, H, Vaisi Raygani, A, Sabokroh, AR, Pourmotabbed, T. Association between apolipoprotein E polymorphism and coronary artery disease in the Kermanshah population in Iran. Clin Biochem, 39 (6), 613-6, 2006.
  25. Raygani, AV, Zahrai, M, Raygani, AV, Doosti, M, Javadi, E, Rezaei, M, Pourmotabbed, T. Association between apolipoprotein E polymorphism and Alzheimer disease in Tehran, Iran. Neurosci Lett, 375 (1), 1-6, 2005.
  26. Duntsch, C, Zhou, Q, Weimar, JD, Frankel, B, Robertson, JH, Pourmotabbed, T. Up-regulation of neuropoiesis generating glial progenitors that infiltrate rat intracranial glioma. J Neurooncol, 71 (3), 245-55, 2005.
  27. Raygani, AV, Zahrai, M, Soltanzadeh, A, Doosti, M, Javadi, E, Pourmotabbed, T. Analysis of association between butyrylcholinesterase K variant and apolipoprotein E genotypes in Alzheimer's disease. Neurosci Lett, 371 (2-3), 142-6, 2004.
  28. Asano, K, Duntsch, CD, Zhou, Q, Weimar, JD, Bordelon, D, Robertson, JH, Pourmotabbed, T. Correlation of N-cadherin expression in high grade gliomas with tissue invasion. J Neurooncol, 70 (1), 3-15, 2004.
  29. Stute, J, Pourmotabbed, T, Tschesche, H. Kinetic analysis of the binding of hemopexin-like domain of gelatinase B cloned and expressed in Pichia pastoris to tissue inhibitor of metalloproteinases-1. J Protein Chem, 22 (6), 509-14, 2003.
  30. Tsukada, H, Pourmotabbed, T. Unexpected crucial role of residue 272 in substrate specificity of fibroblast collagenase. J Biol Chem, 277 (30), 27378-84, 2002.
  31. Kaur, K, Zhu, K, Whittemore, MS, Petersen, RL, Lichte, A, Tschesche, H, Pourmotabbed, T. Identification of the active site of gelatinase B as the structural element sufficient for converting a protein to a metalloprotease. Biochemistry, 41 (15), 4789-97, 2002.
  32. O'Farrell, TJ, Pourmotabbed, T. Identification of structural elements important for matrix metalloproteinase type V collagenolytic activity as revealed by chimeric enzymes. Role of fibronectin-like domain and active site of gelatinase B. J Biol Chem, 275 (36), 27964-72, 2000.
  33. O'Farrell, TJ, Pourmotabbed, T. The fibronectin-like domain is required for the type V and XI collagenolytic activity of gelatinase B. Arch Biochem Biophys, 354 (1), 24-30, 1998.
  34. McCarthy, GM, Macius, AM, Christopherson, PA, Ryan, LM, Pourmotabbed, T. Basic calcium phosphate crystals induce synthesis and secretion of 92 kDa gelatinase (gelatinase B/matrix metalloprotease 9) in human fibroblasts. Ann Rheum Dis, 57 (1), 56-60, 1998.
  35. Hoehn-Saric, R, Hazlett, RL, Pourmotabbed, T, McLeod, DR. Does muscle tension reflect arousal? Relationship between electromyographic and electroencephalographic recordings. Psychiatry Res, 71 (1), 49-55, 1997.
  36. Pourmotabbed, T, Mcleod, DR, Hoehn-Saric, R, Hipsley, P, Greenblatt, DJ. Treatment, discontinuation, and psychomotor effects of diazepam in women with generalized anxiety disorder. J Clin Psychopharmacol, 16 (3), 202-7, 1996.
  37. Bu, CH, Pourmotabbed, T. Mechanism of Ca2+-dependent activity of human neutrophil gelatinase B. J Biol Chem, 271 (24), 14308-15, 1996.
  38. Pourmotabbed, T, Aelion, JA, Tyrrell, D, Hasty, KA, Bu, CH, Mainardi, CL. Role of the conserved histidine and aspartic acid residues in activity and stabilization of human gelatinase B: an example of matrix metalloproteinases. J Protein Chem, 14 (7), 527-35, 1995.
  39. Bu, CH, Pourmotabbed, T. Mechanism of activation of human neutrophil gelatinase B. Discriminating between the role of Ca2+ in activation and catalysis. J Biol Chem, 270 (31), 18563-9, 1995.
  40. Pourmotabbed, T. Relation between substrate specificity and domain structure of 92-kDa type IV collagenase. Ann N Y Acad Sci, 732, 372-4, 1994.
  41. Pourmotabbed, T, Solomon, TL, Hasty, KA, Mainardi, CL. Characteristics of 92 kDa type IV collagenase/gelatinase produced by granulocytic leukemia cells: structure, expression of cDNA in E. coli and enzymic properties. Biochim Biophys Acta, 1204 (1), 97-107, 1994.
  42. Hirose, T, Patterson, C, Pourmotabbed, T, Mainardi, CL, Hasty, KA. Structure-function relationship of human neutrophil collagenase: identification of regions responsible for substrate specificity and general proteinase activity. Proc Natl Acad Sci U S A, 90 (7), 2569-73, 1993.
  43. Mainardi, CL, Pourmotabbed, TF, Hasty, KA. Inflammatory phagocytes and connective tissue degrading metalloproteinases. Am J Med Sci, 302 (3), 171-5, 1991.
  44. Hasty, KA, Pourmotabbed, TF, Goldberg, GI, Thompson, JP, Spinella, DG, Stevens, RM, Mainardi, CL. Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases. J Biol Chem, 265 (20), 11421-4, 1990.
  45. Pourmotabbed, T, Dell'Acqua, M, Gerlt, JA, Stanczyk, SM, Bolton, PH. Kinetic and conformational effects of lysine substitutions for arginines 35 and 87 in the active site of staphylococcal nuclease. Biochemistry, 29 (15), 3677-83, 1990.
  46. Pourmotabbed, T, Shih, MJ, Creighton, DJ. Bovine liver formaldehyde dehydrogenase. Kinetic and molecular properties. J Biol Chem, 264 (29), 17384-8, 1989.
  47. Wilde, JA, Bolton, PH, Hibler, DW, Harpold, L, Pourmotabbed, T, Dell'Acqua, M, Gerlt, JA. Isotopic labeling with hydrogen-2 and carbon-13 to compare conformations of proteins and mutants generated by site-directed mutagenesis, II. Methods Enzymol, 177, 282-92, 1989.
  48. Hibler, DW, Harpold, L, Dell'Acqua, M, Pourmotabbed, T, Gerlt, JA, Wilde, JA, Bolton, PH. Isotopic labeling with hydrogen-2 and carbon-13 to compare conformations of proteins and mutants generated by site-directed mutagenesis, I. Methods Enzymol, 177, 74-86, 1989.
  49. Creighton, DJ, Migliorini, M, Pourmotabbed, T, Guha, MK. Optimization of efficiency in the glyoxalase pathway. Biochemistry, 27 (19), 7376-84, 1988.
  50. Wilde, JA, Bolton, PH, Dell'Acqua, M, Hibler, DW, Pourmotabbed, T, Gerlt, JA. Identification of residues involved in a conformational change accompanying substitutions for glutamate-43 in staphylococcal nuclease. Biochemistry, 27 (11), 4127-32, 1988.
  51. Pourmotabbed, T, Creighton, DJ. Substrate specificity of bovine liver formaldehyde dehydrogenase. J Biol Chem, 261 (30), 14240-4, 1986.