THADDEUS S. NOWAK, Ph.D., B.S.

Professor
Neurology

Office: 415 LINK BUILDING
855 MONROE AVENUE
MEMPHIS TN 381630000
Tel: (901) 448-7384
tnowak@uthsc.edu

Education

  • PostDoc, NINDS, NIH, Bethesda, MD, Neuropathology
  • PostDoc, NINDS, NIH, Bethesda, MD, Neurochemistry
  • Ph.D., Massachusetts Institute of Technology, Physiological Chemistry
  • None, Massachusetts Institute of Technology, Cell Biology
  • B.S., Massachusetts Institute of Technology, Life Sciences

Publications

  1. Takeda, Y, Zhao, L, Jacewicz, M, Pulsinelli, WA, Nowak, TS. Metabolic and perfusion responses to recurrent peri-infarct depolarization during focal ischemia in the Spontaneously Hypertensive Rat: dominant contribution of sporadic CBF decrements to infarct expansion. J Cereb Blood Flow Metab, 31 (9), 1863-73, 2011.
  2. Zhao, Y, Xiao, J, Ueda, M, Wang, Y, Hines, M, Nowak, TS, LeDoux, MS. Glial elements contribute to stress-induced torsinA expression in the CNS and peripheral nervous system. Neuroscience, 155 (2), 439-53, 2008.
  3. Hashimoto, M, Zhao, L, Nowak, TS. Temporal thresholds for infarction and hypothermic protection in Long-Evans rats: factors affecting apparent 'reperfusion injury' after transient focal ischemia. Stroke, 39 (2), 421-6, 2008.
  4. Kurasako, T, Zhao, L, Pulsinelli, WA, Nowak, TS. Transient cooling during early reperfusion attenuates delayed edema and infarct progression in the Spontaneously Hypertensive Rat. Distribution and time course of regional brain temperature change in a model of postischemic hypothermic protection. J Cereb Blood Flow Metab, 27 (12), 1919-30, 2007.
  5. Ma, J, Zhao, L, Nowak, TS. Selective, reversible occlusion of the middle cerebral artery in rats by an intraluminal approach. Optimized filament design and methodology. J Neurosci Methods, 156 (1-2), 76-83, 2006.
  6. Zhao, L, Nowak, TS. CBF changes associated with focal ischemic preconditioning in the spontaneously hypertensive rat. J Cereb Blood Flow Metab, 26 (9), 1128-40, 2006.
  7. Kamiya, T, Jacewicz, M, Nowak, TS, Pulsinelli, WA. Cerebral blood flow thresholds for mRNA synthesis after focal ischemia and the effect of MK-801. Stroke, 36 (11), 2463-7, 2005.
  8. Ueda, M, Nowak, TS. Protective preconditioning by transient global ischemia in the rat: components of delayed injury progression and lasting protection distinguished by comparisons of depolarization thresholds for cell loss at long survival times. J Cereb Blood Flow Metab, 25 (8), 949-58, 2005.
  9. Halaby, IA, Takeda, Y, Yufu, K, Nowak, TS, Pulsinelli, WA. Depolarization thresholds for hippocampal damage, ischemic preconditioning, and changes in gene expression after global ischemia in the rat. Neurosci Lett, 372 (1-2), 12-6, 2004.
  10. Sorimachi, T, Nowak, TS. Pharmacological manipulations of ATP-dependent potassium channels and adenosine A1 receptors do not impact hippocampal ischemic preconditioning in vivo: evidence in a highly quantitative gerbil model. J Cereb Blood Flow Metab, 24 (5), 556-63, 2004.
  11. Nishino, K, Nowak, TS. Time course and cellular distribution of hsp27 and hsp72 stress protein expression in a quantitative gerbil model of ischemic injury and tolerance: thresholds for hsp72 induction and hilar lesioning in the context of ischemic preconditioning. J Cereb Blood Flow Metab, 24 (2), 167-78, 2004.
  12. Abe, H, Nowak, TS. Induced hippocampal neuron protection in an optimized gerbil ischemia model: insult thresholds for tolerance induction and altered gene expression defined by ischemic depolarization. J Cereb Blood Flow Metab, 24 (1), 84-97, 2004.
  13. Ren, Y, Hashimoto, M, Pulsinelli, WA, Nowak, TS. Hypothermic protection in rat focal ischemia models: strain differences and relevance to "reperfusion injury". J Cereb Blood Flow Metab, 24 (1), 42-53, 2004.
  14. Everson, CA, Nowak, TS. Hypothalamic thyrotropin-releasing hormone mRNA responses to hypothyroxinemia induced by sleep deprivation. Am J Physiol Endocrinol Metab, 283 (1), E85-93, 2002.
  15. Marini, AM, Nowak, TS. Metabolic effects of 1-methyl-4-phenylpyridinium (MPP(+)) in primary neuron cultures. J Neurosci Res, 62 (6), 814-20, 2000.
  16. Meade, CA, Figueredo-Cardenas, G, Fusco, F, Nowak, TS, Pulsinelli, WA, Reiner, A. Transient global ischemia in rats yields striatal projection neuron and interneuron loss resembling that in Huntington's disease. Exp Neurol, 166 (2), 307-23, 2000.
  17. Abe, H, Nowak, TS. Postischemic temperature as a modulator of the stress response in brain: dissociation of heat shock protein 72 induction from ischemic tolerance after bilateral carotid artery occlusion in the gerbil. Neurosci Lett, 295 (1-2), 54-8, 2000.
  18. Yufu, K, Yaida, Y, Nowak, TS. Localization of oligonucleotides in brain by in situ hybridization. Methods Enzymol, 314, 238-47, 1999.
  19. Harrub, JB, Nowak, TS. Cryptic expression of the 70-kDa heat shock protein, hsp72, in gerbil hippocampus after transient ischemia. Neurochem Res, 23 (5), 703-8, 1998.
  20. Petito, CK, Olarte, JP, Roberts, B, Nowak, TS, Pulsinelli, WA. Selective glial vulnerability following transient global ischemia in rat brain. J Neuropathol Exp Neurol, 57 (3), 231-8, 1998.
  21. Suga S, Nowak TS Jr.. Postischemic hyperthermia increases expression of hsp72 mRNA after brief ischemia in the gerbil.. Neurosci Lett., 243(1-3), 57-60, 1998.