TERRENCE L. GEIGER, Ph.D., M.D.

Professor
Pathology

Office:
Tel: n/a
n/a

My Current CV

Publications

  1. Inaba, H, Steeves, M, Nguyen, P, Geiger, TL. In vivo suppression of naive CD4 T cell responses by IL-2- and antigen-stimulated T lymphocytes in the absence of APC competition. J Immunol, 181 (5), 3323-35, 2008.
  2. Inaba, H, Fan, Y, Pounds, S, Geiger, TL, Rubnitz, JE, Ribeiro, RC, Pui, CH, Razzouk, BI. Clinical and biologic features and treatment outcome of children with newly diagnosed acute myeloid leukemia and hyperleukocytosis. Cancer, 113 (3), 522-9, 2008.
  3. Alli, R, Nguyen, P, Geiger, TL. Retrogenic modeling of experimental allergic encephalomyelitis associates T cell frequency but not TCR functional affinity with pathogenicity. J Immunol, 181 (1), 136-45, 2008.
  4. Moisini, I, Nguyen, P, Fugger, L, Geiger, TL. Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-zeta chimeric receptor. J Immunol, 180 (5), 3601-11, 2008.
  5. Selvaraj, RK, Geiger, TL. Mitigation of experimental allergic encephalomyelitis by TGF-beta induced Foxp3+ regulatory T lymphocytes through the induction of anergy and infectious tolerance. J Immunol, 180 (5), 2830-8, 2008.
  6. Nguyen, P, Duthoit, CT, Geiger, TL. Induction of tolerance and immunity by redirected B cell-specific cytolytic T lymphocytes. Gene Ther, 14 (24), 1739-49, 2007.
  7. Selvaraj, RK, Geiger, TL. A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta. J Immunol, 179 (2), 11 p following 1390, 2007.
  8. Selvaraj, RK, Geiger, TL. A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta. J Immunol, 178 (12), 7667-77, 2007.
  9. Sanders, RP, Geiger, TL, Heddle, N, Pui, CH, Howard, SC. A revised classification scheme for acute transfusion reactions. Transfusion, 47 (4), 621-8, 2007.
  10. Geiger, TL, Howard, SC. Acetaminophen and diphenhydramine premedication for allergic and febrile nonhemolytic transfusion reactions: good prophylaxis or bad practice. Transfus Med Rev, 21 (1), 1-12, 2007.
  11. Inaba, H, Geiger, TL. Defective cell cycle induction by IL-2 in naive T-cells antigen stimulated in the presence of refractory T-lymphocytes. Int Immunol, 18 (7), 1043-54, 2006.
  12. Sanders, RP, Maddirala, SD, Geiger, TL, Pounds, S, Sandlund, JT, Ribeiro, RC, Pui, CH, Howard, SC. Premedication with acetaminophen or diphenhydramine for transfusion with leucoreduced blood products in children. Br J Haematol, 130 (5), 781-7, 2005.
  13. Mekala, DJ, Alli, RS, Geiger, TL. IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Proc Natl Acad Sci U S A, 102 (33), 11817-22, 2005.
  14. Lowe, EJ, Pui, CH, Hancock, ML, Geiger, TL, Khan, RB, Sandlund, JT. Early complications in children with acute lymphoblastic leukemia presenting with hyperleukocytosis. Pediatr Blood Cancer, 45 (1), 10-5, 2005.
  15. Mekala, DJ, Alli, RS, Geiger, TL. IL-10-dependent suppression of experimental allergic encephalomyelitis by Th2-differentiated, anti-TCR redirected T lymphocytes. J Immunol, 174 (6), 3789-97, 2005.
  16. Mekala, DJ, Geiger, TL. Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Blood, 105 (5), 2090-2, 2005.
  17. Inaba, H, Geiger, TL, Lasater, OE, Wang, WC. A case of hemoglobin SC disease with cold agglutinin-induced hemolysis. Am J Hematol, 78 (1), 37-40, 2005.
  18. Duthoit, CT, Mekala, DJ, Alli, RS, Geiger, TL. Uncoupling of IL-2 signaling from cell cycle progression in naive CD4+ T cells by regulatory CD4+CD25+ T lymphocytes. J Immunol, 174 (1), 155-63, 2005.
  19. Imai, C, Mihara, K, Andreansky, M, Nicholson, IC, Pui, CH, Geiger, TL, Campana, D. Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia. Leukemia, 18 (4), 676-84, 2004.
  20. Duthoit, CT, Nguyen, P, Geiger, TL. Antigen nonspecific suppression of T cell responses by activated stimulation-refractory CD4+ T cells. J Immunol, 172 (4), 2238-46, 2004.
  21. Carpino, N, Turner, S, Mekala, D, Takahashi, Y, Zang, H, Geiger, TL, Doherty, P, Ihle, JN. Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2. Immunity, 20 (1), 37-46, 2004.
  22. Nguyen, P, Moisini, I, Geiger, TL. Identification of a murine CD28 dileucine motif that suppresses single-chain chimeric T-cell receptor expression and function. Blood, 102 (13), 4320-5, 2003.
  23. Iyengar, R, Handgretinger, R, Babarin-Dorner, A, Leimig, T, Otto, M, Geiger, TL, Holladay, MS, Houston, J, Leung, W. Purification of human natural killer cells using a clinical-scale immunomagnetic method. Cytotherapy, 5 (6), 479-84, 2003.
  24. Mekala, DJ, Geiger, TL. Functional segregation of the TCR and antigen-MHC complexes on the surface of CTL. J Immunol, 171 (8), 4089-95, 2003.
  25. Nguyen, P, Geiger, TL. Antigen-specific targeting of CD8+ T cells with receptor-modified T lymphocytes. Gene Ther, 10 (7), 594-604, 2003.
  26. Jyothi, MD, Flavell, RA, Geiger, TL. Targeting autoantigen-specific T cells and suppression of autoimmune encephalomyelitis with receptor-modified T lymphocytes. Nat Biotechnol, 20 (12), 1215-20, 2002.
  27. Geiger, TL, Woodard, P, Tong, X, Srivastava, DK, Johnson, R, Turner, V, Hale, G, Richardson, S. Human leucocyte antigen alloimmunization after bone marrow transplantation: an association with chronic myelogenous leukaemia. Br J Haematol, 117 (3), 634-41, 2002.
  28. Molnar, R, Johnson, R, Sweat, LT, Geiger, TL. Absence of D alloimmunization in D- pediatric oncology patients receiving D-incompatible single-donor platelets. Transfusion, 42 (2), 177-82, 2002.
  29. Geiger, TL, Nguyen, P, Leitenberg, D, Flavell, RA. Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes. Blood, 98 (8), 2364-71, 2001.
  30. Geiger, TL, Jyothi, MD. Development and application of receptor-modified T lymphocytes for adoptive immunotherapy. Transfus Med Rev, 15 (1), 21-34, 2001.