Research Asst Professor
Pharmaceutical Sciences

Office: 327 Johnson Building
Tel: (901) 448-7837


  1. Patil, R, Hosni-Ahmed, A, Jones, TS, Patil, SA, Asres, LB, Wang, X, Yates, RC, Geisert, EE, Miller, DD. Synthesis and in vitro evaluation of novel 1,2,3,4-tetrahydroisoquinoline derivatives as potent antiglioma agents. Anticancer Agents Med Chem, 14 (3), 473-82, 2014.
  2. Patil, SA, Hosni-Ahmed, A, Jones, TS, Patil, R, Pfeffer, LM, Miller, DD. Novel approaches to glioma drug design and drug screening. Expert Opin Drug Discov, 2013.
  3. Bukiya, AN, McMillan, JE, Fedinec, AL, Patil, SA, Miller, DD, Leffler, CW, Parrill, AL, Dopico, AM. Cerebrovascular Dilation via Selective Targeting of the Cholane Steroid-Recognition Site in the BK Channel β1-Subunit by a Novel Nonsteroidal Agent. Mol Pharmacol, 83 (5), 1030-44, 2013.
  4. Patil SA, Patil R, Pfeffer LM, Miller DD.. Chromenes: potential new chemotherapeutic agents for cancer. Future Medicinal Chemistry, 2013.
  5. Shivaputra A. Patil and Duane D. Miller. Current Trends in Medicinal Chemistry. Organic Chemistry: Current Research, 2, e124, 2013.
  6. Bukiya AN, Patil SA, Li W, Miller DD, Dopico AM.. Structural Requirements in the Steroid Lateral Chain for the Activation of β1 Subunit-Containing BK Channels by 5β-Cholanic Acid-3α-Ol Analogues.. Biophysical Journal, 104 (2), 472a, 2013.
  7. Patil, SA, Patil, R, Miller, DD. Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents. Future Med Chem, 4 (16), 2085-115, 2012.
  8. Bukiya, AN, Patil, SA, Li, W, Miller, DD, Dopico, AM. Calcium- and voltage-gated potassium (BK) channel activators in the 5β-cholanic acid-3α-ol analogue series with modifications in the lateral chain. ChemMedChem, 7 (10), 1784-92, 2012.
  9. Wang, XD, Freeman, NE, Patil, R, Patil, SA, Mitra, S, Orr, WE, Abner, CW, Yates, CR, Miller, DD, Geisert, EE. EDL-291, a novel isoquinoline, presents antiglioblastoma effects in vitro and in vivo. Anticancer Drugs, 23 (5), 494-504, 2012.
  10. Mohler, ML, Coss, CC, Duke, CB, Patil, SA, Miller, DD, Dalton, JT. Androgen receptor antagonists: a patent review (2008 - 2011). Expert Opin Ther Pat, 22 (5), 541-65, 2012.
  11. Patil SA, Wang J, Li XS, Chen J, Jones TS, Hosni-Ahmed A, Patil R, Seibel WL, Li W, Miller DD. New substituted 4H-chromenes as anticancer agents. Bioorg Med Chem Lett., 22 (13), 4458-4461, 2012.
  12. Patil SA. Role of Medicinal Chemist in the Modern Drug Discovery and Development.. Organic Chemistry: Current Research Journal, 1, e110, 2012.
  13. Sharma, H, Patil, S, Sanchez, TW, Neamati, N, Schinazi, RF, Buolamwini, JK. Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors. Bioorg Med Chem, 19 (6), 2030-45, 2011.
  14. Patil, R, Patil, S, Wang, XD, Ma, F, Orr, E, Li, W, Yates, CR, Geisert, EE, Miller, DD.. Synthesis and evaluation of new 1,2,3,4-tetrahydroisoquinoline analogs as antiglioma agents. MedChemRes, 20 (1), 131-137, 2011.
  15. Patil SA, Patil R, Miller DD. Microwave-assisted synthesis of medicinally relevant indoles. Curr Med Chem., 18 (4), 615-37, 2011.
  16. Patil, SA, Patil, R, Miller, DD. Solid phase synthesis of biologically important indoles. Curr Med Chem, 16 (20), 2531-65, 2009.
  17. Patil, S, Bukiya, AN, Li, W, Dopico, AM, Miller, D. Design and synthesis of hydroxy-alkynoic acids and their methyl esters as novel activators of BK channels. Bioorg Med Chem Lett, 18 (11), 3427-30, 2008.
  18. Luo, W, Liu, J, Li, J, Zhang, D, Liu, M, Addo, JK, Patil, S, Zhang, L, Yu, J, Buolamwini, JK, Chen, J, Huang, C. Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway. J Biol Chem, 283 (13), 8624-33, 2008.
  19. Patil SA, Patil R, Miller DD. Synthetic applications of the Nenitzescu reaction to biologically active 5-hydroxyindoles. CurrOrgChem, 12 (9), 691-717, 2008.
  20. Patil, S, Kamath, S, Sanchez, T, Neamati, N, Schinazi, RF, Buolamwini, JK. Synthesis and biological evaluation of novel 5(H)-phenanthridin-6-ones, 5(H)-phenanthridin-6-one diketo acid, and polycyclic aromatic diketo acid analogs as new HIV-1 integrase inhibitors. Bioorg Med Chem, 15 (3), 1212-28, 2007.
  21. Patil SA, Patil R.. Synthesis and functionalization of indoles through rhodium-catalyzed reactions. CurrOrgSyn, 4 (2), 201-222, 2007.
  22. Patil SA, Buolamwini JK.. Recent uses of palladium chemistry in indole synthesis. CurrOrgSyn, 3 (4), 477-498, 2006.
  23. Buolamwini, JK, Addo, J, Kamath, S, Patil, S, Mason, D, Ores, M. Small molecule antagonists of the MDM2 oncoprotein as anticancer agents. Curr Cancer Drug Targets, 5 (1), 57-68, 2005.
  24. Dinsmore, A, Billing, DG, Mandy, K, Michael, JP, Mogano, D, Patil, S. Magnesiation employing Grignard reagents and catalytic amine. Application to the functionalization of N-phenylsulfonylpyrrole. Org Lett, 6 (2), 293-6, 2004.
  25. Guru S. Gadaginamth and Shivaputra A. Patil.. Synthesis and antimicrobial activity of 6-bromo-1-butyl-3-ethoxycarbonyl-2-(n-methyl-N-phenylamino) methyl-5(1,2,3,4-tetrazol-5-yl)methoxyindole.. Revue Roumaine de Chimie, 46 (2), 99-102, 2001.
  26. Guru S. Gadaginamth, Rajesh. R. Kavali, Shivaputra A. Patil and A. S. Shyadligeri. One pot synthesis of novel 5,11-dioxo-6-methyl-5,9,10,11-tetrahydro-8H-napth[2,3:1,2]pyrrolizine and its 9-acetoxy analogue.. Indian J. Chem, 38B, 1123-1125, 1999.
  27. G.S. Gadaginamath and S.A. Patil. Synthesis and Antibacterial Activity of Novel 1-Butyl-2-phenoxy/2-Phenylthio/2-Aminomethyl-5- - methoxyindole Derivatives. Polish J.Chem, 71, 932-938, 1997.