
SARKA BERANOVA-GIORGIANNI, Ph.D.
Associate Professor
Pharmaceutical Sciences
Assistant Professor
Neurology
![]() 881 MADISON AVENUE MEMPHIS TN 381630000 ![]() ![]() |
Education
- Ph.D., University of Akron, Akron, Ohio, Analytical chemistry
- M.S., University of Chemistry and Technology, Prague, Czechoslovakia, Organic chemistry
Research Keywords
bioanalytical chemistry; mass spectrometry; proteomics; phosphoproteomics
Research Interest/Specialty
Bioanalytical chemistry; biological mass spectrometry; qualitative and quantitative proteomics; targeted protein and phosphoprotein identification/characterization.
Research Description
- Proteomics of the retina in health and disease
- Phosphoproteomics of the mammalian pituitary
- High-sensitivity phosphoprotein characterization
- Design and development of new and improved analytical platforms for proteomics.
Publications
- Donato, L, Bramanti, P, Scimone, C, Rinaldi, C, Giorgianni, F, Beranova-Giorgianni, S, Koirala, D, D'Angelo, R, Sidoti, A. Corrigendum to: miRNA expression profile of retinal pigment epithelial cells under oxidative stress conditions. FEBS Open Bio, 8 (11), 1884, 2018.
- Koirala, D, Beranova-Giorgianni, S, Giorgianni, F. Data-independent proteome analysis of ARPE-19 cells. Data Brief, 20, 333-336, 2018.
- Hollingsworth, TJ, Radic, MZ, Beranova-Giorgianni, S, Giorgianni, F, Wang, Y, Iannaccone, A. Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4). Invest Ophthalmol Vis Sci, 59 (10), 3808-3815, 2018.
- Beranova-Giorgianni, S, Giorgianni, F. Proteomics of Human Retinal Pigment Epithelium (RPE) Cells. Proteomes, 6 (2), 2018.
- Beranova-Giorgianni, S. Connecting non-pharmacist faculty to pharmacy practice. Curr Pharm Teach Learn, 10 (5), 546-548, 2018.
- Iannaccone, A, Hollingsworth, TJ, Koirala, D, New, DD, Lenchik, NI, Beranova-Giorgianni, S, Gerling, IC, Radic, MZ, Giorgianni, F. Retinal pigment epithelium and microglia express the CD5 antigen-like protein, a novel autoantigen in age-related macular degeneration. Exp Eye Res, 155, 64-74, 2017.
- Giorgianni, F, Beranova-Giorgianni, S. Phosphoproteome Discovery in Human Biological Fluids. Proteomes, 4 (4), 2016.
- Iannaccone, A, Giorgianni, F, New, DD, Hollingsworth, TJ, Umfress, A, Alhatem, AH, Neeli, I, Lenchik, NI, Jennings, BJ, Calzada, JI, Satterfield, S, Mathews, D, Diaz, RI, Harris, T, Johnson, KC, Charles, S, Kritchevsky, SB, Gerling, IC, Beranova-Giorgianni, S, Radic, MZ, ,. Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis. PLoS One, 10 (12), e0145323, 2015.
- Dong, Q, Giorgianni, F, Beranova-Giorgianni, S, Deng, X, O'Meally, RN, Bridges, D, Park, EA, Cole, RN, Elam, MB, Raghow, R. Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradation. Biosci Rep, 36 (1), e00284, 2015.
- Giorgianni, F, Koirala, D, Beranova-Giorgianni, S. Proteomics of the human pituitary tissue: bioanalytical methods and applications. Bioanalysis, 6 (14), 1989-2003, 2014.
- Dong, Q, Giorgianni, F, Deng, X, Beranova-Giorgianni, S, Bridges, D, Park, EA, Raghow, R, Elam, MB. Phosphorylation of sterol regulatory element binding protein-1a by protein kinase A (PKA) regulates transcriptional activity. Biochem Biophys Res Commun, 449 (4), 449-54, 2014.
- Giorgianni, F, Koirala, D, Weber, KT, Beranova-Giorgianni, S. Proteome analysis of subsarcolemmal cardiomyocyte mitochondria: a comparison of different analytical platforms. Int J Mol Sci, 15 (6), 9285-301, 2014.
- Giorgianni, F, Usman Khan, M, Weber, KT, Gerling, IC, Beranova-Giorgianni, S. Phosphoproteome mapping of cardiomyocyte mitochondria in a rat model of heart failure. Mol Cell Biochem, 389 (1-2), 159-67, 2014.
- Giorgianni, F, Mileo, V, Desiderio, DM, Catinella, S, Beranova-Giorgianni, S. Characterization of the phosphoproteome in human bronchoalveolar lavage fluid. Int J Proteomics, 2012, 460261, 2012.
- Chen, L, Fang, B, Giorgianni, F, Gingrich, JR, Beranova-Giorgianni, S. Investigation of phosphoprotein signatures of archived prostate cancer tissue specimens via proteomic analysis. Electrophoresis, 32 (15), 1984-91, 2011.
- Bolen, AL, Naren, AP, Yarlagadda, S, Beranova-Giorgianni, S, Chen, L, Norman, D, Baker, DL, Rowland, MM, Best, MD, Sano, T, Tsukahara, T, Liliom, K, Igarashi, Y, Tigyi, G. The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation. J Lipid Res, 52 (5), 958-70, 2011.
- Wang, X, Tong, Y, Giorgianni, F, Beranova-Giorgianni, S, Penn, JS, Jablonski, MM. Cellular retinol binding protein 1 modulates photoreceptor outer segment folding in the isolated eye. Dev Neurobiol, 70 (9), 623-35, 2010.
- Nookala, S, Gandrakota, R, Wohabrebbi, A, Wang, X, Howell, D, Giorgianni, F, Beranova-Giorgianni, S, Desiderio, DM, Jablonski, MM. In search of the identity of the XAP-1 antigen: a protein localized to cone outer segments. Invest Ophthalmol Vis Sci, 51 (5), 2736-43, 2010.
- Chen, L, Giorgianni, F, Beranova-Giorgianni, S. Characterization of the phosphoproteome in LNCaP prostate cancer cells by in-gel isoelectric focusing and tandem mass spectrometry. J Proteome Res, 9 (1), 174-8, 2010.
- Beranova-Giorgianni, S, Desiderio, DM, Giorgianni, F. Phosphoproteome analysis by in-gel isoelectric focusing and tandem mass spectrometry. Methods Mol Biol, 519, 383-96, 2009.
- Wang, X, Nookala, S, Narayanan, C, Giorgianni, F, Beranova-Giorgianni, S, McCollum, G, Gerling, I, Penn, JS, Jablonski, MM. Proteomic analysis of the retina: removal of RPE alters outer segment assembly and retinal protein expression. Glia, 57 (4), 380-92, 2009.
- Pabst, MJ, Pabst, KM, Handsman, DB, Beranova-Giorgianni, S, Giorgianni, F. Proteome of monocyte priming by lipopolysaccharide, including changes in interleukin-1beta and leukocyte elastase inhibitor. Proteome Sci, 6, 13, 2007.
- Giorgianni, F, Zhao, Y, Desiderio, DM, Beranova-Giorgianni, S. Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line. Electrophoresis, 28 (12), 2027-34, 2007.
- Beranova-Giorgianni, S, Zhao, Y, Desiderio, DM, Giorgianni, F. Phosphoproteomic analysis of the human pituitary. Pituitary, 9 (2), 109-20, 2006.
- Zhao, Y, Giorgianni, F, Desiderio, DM, Fang, B, Beranova-Giorgianni, S. Toward a global analysis of the human pituitary proteome by multiple gel-based technology. Anal Chem, 77 (16), 5324-31, 2005.
- Giorgianni, F, Cappiello, A, Beranova-Giorgianni, S, Palma, P, Trufelli, H, Desiderio, DM. LC-MS/MS analysis of peptides with methanol as organic modifier: improved limits of detection. Anal Chem, 76 (23), 7028-38, 2004.
- Giorgianni, F, Beranova-Giorgianni, S, Desiderio, DM. Identification and characterization of phosphorylated proteins in the human pituitary. Proteomics, 4 (3), 587-98, 2004.
- Gadgil, HS, Pabst, KM, Giorgianni, F, Umstot, ES, Desiderio, DM, Beranova-Giorgianni, S, Gerling, IC, Pabst, MJ. Proteome of monocytes primed with lipopolysaccharide: analysis of the abundant proteins. Proteomics, 3 (9), 1767-80, 2003.
- Giorgianni, F, Desiderio, DM, Beranova-Giorgianni, S. Proteome analysis using isoelectric focusing in immobilized pH gradient gels followed by mass spectrometry. Electrophoresis, 24 (1-2), 253-9, 2003.
- Beranova-Giorgianni, S, Giorgianni, F, Desiderio, DM. Analysis of the proteome in the human pituitary. Proteomics, 2 (5), 534-42, 2002.