Smith, Richard A., Ph.D.

Associate Professor
Graduate Program Director
Orthopaedic Surgery &
Biomedical Engineering and Imaging

Office: A302 Coleman College Of Medicine Building
Tel: (901) 448-5254


  1. Schwab, LP, Marlar, J, Hasty, KA, Smith, RA. Macrophage response to high number of titanium particles is cytotoxic and COX-2 mediated and it is not affected by the particle's endotoxin content or the cleaning treatment. J Biomed Mater Res A, 99 (4), 630-7, 2011.
  2. Slominski, AT, Li, W, Bhattacharya, SK, Smith, RA, Johnson, PL, Chen, J, Nelson, KE, Tuckey, RC, Miller, D, Jiao, Y, Gu, W, Postlethwaite, AE. Vitamin D analogs 17,20S(OH)2pD and 17,20R(OH)2pD are noncalcemic and exhibit antifibrotic activity. J Invest Dermatol, 131 (5), 1167-9, 2011.
  3. Smith, RA, Maghsoodpour, A, Hallab, NJ. In vivo response to cross-linked polyethylene and polycarbonate-urethane particles. J Biomed Mater Res A, 93 (1), 227-34, 2010.
  4. Smith, RA, Hallab, NJ. In vitro macrophage response to polyethylene and polycarbonate-urethane particles. J Biomed Mater Res A, 93 (1), 347-55, 2010.
  5. Cummings, JE, Smith, RA, Heck, RK. Argon beam coagulation as adjuvant treatment after curettage of aneurysmal bone cysts: a preliminary study. Clin Orthop Relat Res, 468 (1), 231-7, 2010.
  6. Heck, RK, Pope, WD, Ahn, JI, Smith, RA, Webber, BL. Histologic evaluation of the depth of necrosis produced by argon beam coagulation: implications for use as adjuvant treatment of bone tumors. J Surg Orthop Adv, 18 (2), 69-73, 2009.
  7. Xing, Z, Schwab, LP, Alley, CF, Hasty, KA, Smith, RA. Titanium particles that have undergone phagocytosis by macrophages lose the ability to activate other macrophages. J Biomed Mater Res B Appl Biomater, 85 (1), 37-41, 2008.
  8. Xing, Z, Hasty, KA, Smith, RA. Administration of pamidronate alters bone-titanium attachment in the presence of endotoxin-coated polyethylene particles. J Biomed Mater Res B Appl Biomater, 83 (2), 354-8, 2007.
  9. Donley BG, Moore T, Sferra J, Gozdanovic J, Smith R.. The efficacy of oral nonsteroidal anti-inflammatory medication (NSAID) in the treatment of plantar fasciitis: a randomized, prospective, placebo-controlled study. Foot Ankle Int., 1 (28), 20-23, 2007.
  10. Myers, LK, Bhattacharya, SD, Herring, PA, Xing, Z, Goorha, S, Smith, RA, Bhattacharya, SK, Carbone, L, Faccio, R, Kang, AH, Ballou, LR. The isozyme-specific effects of cyclooxygenase-deficiency on bone in mice. Bone, 39 (5), 1048-52, 2006.
  11. Schwab, LP, Xing, Z, Hasty, KA, Smith, RA. Titanium particles and surface-bound LPS activate different pathways in IC-21 macrophages. J Biomed Mater Res B Appl Biomater, 79 (1), 66-73, 2006.
  12. Xing, Z, Pabst, MJ, Hasty, KA, Smith, RA. Accumulation of LPS by polyethylene particles decreases bone attachment to implants. J Orthop Res, 24 (5), 959-66, 2006.
  13. Ahn, Jae I., Erdin, Robert A., Smith, Richard A., Canale, S. Terry, Hasty, Karen A. Chondrocyte Injection in Distraction Epiphysiolysis (Rabbit model). Journal of Orthopaedic Research, 3 (24), 355-365, 2006.
  14. Hatori M, Kotajima S, Smith RA, Kokubun S. Ankle dislocation without accompanying malleolar fracture. A case report.. Ups J Med Sci, 2 (111), 263-268, 2006.
  15. Hatori M, Goto M, Tanaka K, Smith RA, Kokubun S. Neglected irreducible dislocation of the interphalangeal joint of the great toe: a case report. J Foot Ankle Surg, 4 (45), 271-274, 2006.
  16. Chhokar, VS, Sun, Y, Bhattacharya, SK, Ahokas, RA, Myers, LK, Xing, Z, Smith, RA, Gerling, IC, Weber, KT. Hyperparathyroidism and the calcium paradox of aldosteronism. Circulation, 111 (7), 871-8, 2005.
  17. Hattori, K. Hatori M, Hosaka M, Watanabe M. Smith, RA, Kokubun. Spindle Cell Lipoma Showing Biphasic Pattern. A Case Report.. Upsala J Med Sci, 110, 173-178, 2005.
  18. Chhokar, VS, Sun, Y, Bhattacharya, SK, Ahokas, RA, Myers, LK, Xing, Z, Smith, RA, Gerling, IC, Weber, KT. Loss of bone minerals and strength in rats with aldosteronism. Am J Physiol Heart Circ Physiol, 287 (5), H2023-6, 2004.
  19. Hatori M, Miyasaka Y, Kimura I, Smith RA, Kokubun S. Field distribution of compound muscle action potentials of the calf muscles in rabbits. Ups J Med Sci, 2 (109), 131-9, 2004.
  20. Hosaka M, Hatori M, Smith, RA, Kokubun S. Giant cell formation through fusion of cells derived from a human giant cell tumor of tendon sheath.. Journal of Orthopaedic Science, 9, 581-584, 2004.
  21. Hiroshi Kato, Masahito Hatori, Shoichi Kokubun, Mika Watanabe, Richard A. Smith, Tetsuo Hotta, Akira Ogose, Tetsuro Morita, Takashi Murakami and Setsuya Aiba. CA125 Expression in Epithelioid Sarcoma. Jpn J Clin Oncol, 3 (34), 149-154, 2004.
  22. Hardison, A, Lewis, G, Daniels, AU, Smith, RA. Determination of the activation energies of and aggregate rates for exothermic physico-chemical changes in UHMWPE by isothermal heat-conduction microcalorimetry (IHCMC). Biomaterials, 24 (28), 5145-51, 2003.
  23. Kumar, A, Charlebois, SJ, Cain, EL, Smith, RA, Daniels, AU, Crates, JM. Effect of fibular plate fixation on rotational stability of simulated distal tibial fractures treated with intramedullary nailing. J Bone Joint Surg Am, 85-A (4), 604-8, 2003.
  24. Charlebois, SJ, Daniels, AU, Smith, RA. Metabolic heat production as a measure of macrophage response to particles from orthopedic implant materials. J Biomed Mater Res, 59 (1), 166-75, 2002.
  25. Smith, RA, Ingels, J, Lochemes, JJ, Dutkowsky, JP, Pifer, LL. Gamma irradiation of HIV-1. J Orthop Res, 19 (5), 815-9, 2001.
  26. Smith, RA, Rooney, MM, Lord, ST, Mosesson, MW, Gartner, TK. Evidence for new endothelial cell binding sites on fibrinogen. Thromb Haemost, 84 (5), 819-25, 2000.
  27. Smith, RA, Mosesson, MW, Daniels, AU, Gartner, TK. Adhesion of microvascular endothelial cells to metallic implant surfaces. J Mater Sci Mater Med, 11 (5), 279-85, 2000.
  28. Daniels, AU, Barnes, FH, Charlebois, SJ, Smith, RA. Macrophage cytokine response to particles and lipopolysaccharide in vitro. J Biomed Mater Res, 49 (4), 469-78, 2000.
  29. Smith, RA, Mosesson, MW, Rooney, MM, Lord, ST, Daniels, AU, Gartner, TK. The role of putative fibrinogen Aalpha-, Bbeta-, and GammaA-chain integrin binding sites in endothelial cell-mediated clot retraction. J Biol Chem, 272 (35), 22080-5, 1997.
  30. Becker, PL, Smith, RA, Williams, RS, Dutkowsky, JP. Comparison of antibiotic release from polymethylmethacrylate beads and sponge collagen. J Orthop Res, 12 (5), 737-41, 1994.
  31. Dutkowsky, JP, Smith, RA, Calandruccio, RA, Carnesale, PG. Effect of fetal thyroid hormone (RT3) on sarcoma cells in culture. J Orthop Res, 11 (3), 379-85, 1993.
  32. Prieskorn, David, Graves, Stanley C., and Smith, Richard A.. Morphometric Analysis of Plantar Plate Apparatus of the First Metatarsophalangeal Joint.. Foot and Ankle, 4 (14), 204-207, 1993.
  33. Hatori, Masahito, Dutkowsky, Joseph P., Smith, Richard A. Tissue Distribution of 125I-Labeled Fetal Thyroid Hormone in Nude Mice Xenografted with Ewing Sarcoma.. Tohoku Journal of Experimental Medicine, 167, 239-242, 1992.
  34. O'Toole, ML, Hiller, WD, Smith, RA, Sisk, TD. Overuse injuries in ultraendurance triathletes. Am J Sports Med, 17 (4), 514-8, 1989.