PATRICIA MICHELE FLYNN, M.D., B.S.

Professor
Pediatrics-Administration

Office: ST JUDE CHILDREN'S RESEARCH HOSPITAL
332 NORTH LAUDERDALE STREET
MEMPHIS TN 381052794
Tel: (901) 495-3486
n/a

Education

  • M.S., University of Tennessee Health Science Center, Memphis, TN, Epidemiology
  • M.D., Louisiana State University Medical Center, New Orleans, LA, Medicine
  • B.S., Rhodes College, Memphis, TN, Chemistry

Research description

Hepatitis B vaccination in HIV-infected youth: improve outreach and testing.

Research description

Hepatitis B vaccination in HIV-infected youth: improve outreach and testing.

Publications

  1. Flynn, PM, Rodman, J, Lindsey, JC, Robbins, B, Capparelli, E, Knapp, KM, Rodriguez, JF, McNamara, J, Serchuck, L, Heckman, B, Martinez, J, ,. Intracellular pharmacokinetics of once versus twice daily zidovudine and lamivudine in adolescents. Antimicrob Agents Chemother, 51 (10), 3516-22, 2007.
  2. Flynn, PM, Rudy, BJ, Lindsey, JC, Douglas, SD, Lathey, J, Spector, SA, Martinez, J, Silio, M, Belzer, M, Friedman, L, D'Angelo, L, Smith, E, Hodge, J, Hughes, MD, ,. Long-term observation of adolescents initiating HAART therapy: three-year follow-up. AIDS Res Hum Retroviruses, 23 (10), 1208-14, 2007.
  3. Madden, RM, Pui, CH, Hughes, WT, Flynn, PM, Leung, W. Prophylaxis of Pneumocystis carinii pneumonia with atovaquone in children with leukemia. Cancer, 109 (8), 1654-8, 2007.
  4. Kadivar, H, Garvie, PA, Sinnock, C, Heston, JD, Flynn, PM. Psychosocial profile of HIV-infected adolescents in a Southern US urban cohort. AIDS Care, 18 (6), 544-9, 2006.
  5. Knapp, KM, Flynn, PM. Newer treatments for fungal infections. J Support Oncol, 3 (4), 290-8, 2005.
  6. Gaur, AH, Flynn, PM, Heine, DJ, Giannini, MA, Shenep, JL, Hayden, RT. Diagnosis of catheter-related bloodstream infections among pediatric oncology patients lacking a peripheral culture, using differential time to detection. Pediatr Infect Dis J, 24 (5), 445-9, 2005.
  7. Gaur, AH, Flynn, PM, Shenep, JL. Optimum management of pediatric patients with fever and neutropenia. Indian J Pediatr, 71 (9), 825-35, 2004.
  8. Flynn, PM, Rudy, BJ, Douglas, SD, Lathey, J, Spector, SA, Martinez, J, Silio, M, Belzer, M, Friedman, L, D'Angelo, L, McNamara, J, Hodge, J, Hughes, MD, Lindsey, JC, ,. Virologic and immunologic outcomes after 24 weeks in HIV type 1-infected adolescents receiving highly active antiretroviral therapy. J Infect Dis, 190 (2), 271-9, 2004.
  9. Franklin, JA, Gaur, AH, Shenep, JL, Hu, XJ, Flynn, PM. In situ diagnosis of central venous catheter-related bloodstream infection without peripheral blood culture. Pediatr Infect Dis J, 23 (7), 614-8, 2004.
  10. McCarty, ML, Wilson, MW, Fleming, JC, Thompson, JW, Sandlund, JT, Flynn, PM, Knapp, KM, Haik, BG, Ribeiro, RC. Manifestations of fungal cellulitis of the orbit in children with neutropenia and fever. Ophthal Plast Reconstr Surg, 20 (3), 217-23, 2004.
  11. Flynn, PM, Willis, B, Gaur, AH, Shenep, JL. Catheter design influences recurrence of catheter-related bloodstream infection in children with cancer. J Clin Oncol, 21 (18), 3520-5, 2003.
  12. Gaur, AH, Flynn, PM, Giannini, MA, Shenep, JL, Hayden, RT. Difference in time to detection: a simple method to differentiate catheter-related from non-catheter-related bloodstream infection in immunocompromised pediatric patients. Clin Infect Dis, 37 (4), 469-75, 2003.
  13. Franklin, JA, McCormick, J, Flynn, PM. Retrospective study of the safety of caspofungin in immunocompromised pediatric patients. Pediatr Infect Dis J, 22 (8), 747-9, 2003.
  14. Gaur, AH, Giannini, MA, Flynn, PM, Boudreaux, JW, Mestemacher, MA, Shenep, JL, Hayden, RT. Optimizing blood culture practices in pediatric immunocompromised patients: evaluation of media types and blood culture volume. Pediatr Infect Dis J, 22 (6), 545-52, 2003.
  15. van de Poll, ME, Relling, MV, Schuetz, EG, Harrison, PL, Hughes, W, Flynn, PM. The effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemia. Cancer Chemother Pharmacol, 47 (6), 467-72, 2001.
  16. Gaur, AH, Patrick, CC, McCullers, JA, Flynn, PM, Pearson, TA, Razzouk, BI, Thompson, SJ, Shenep, JL. Bacillus cereus bacteremia and meningitis in immunocompromised children. Clin Infect Dis, 32 (10), 1456-62, 2001.
  17. Hoffer, FA, Gow, K, Flynn, PM, Davidoff, A. Accuracy of percutaneous lung biopsy for invasive pulmonary aspergillosis. Pediatr Radiol, 31 (3), 144-52, 2001.
  18. Shenep, JL, Flynn, PM, Baker, DK, Hetherington, SV, Hudson, MM, Hughes, WT, Patrick, CC, Roberson, PK, Sandlund, JT, Santana, VM, Sixbey, JW, Slobod, KS. Oral cefixime is similar to continued intravenous antibiotics in the empirical treatment of febrile neutropenic children with cancer. Clin Infect Dis, 32 (1), 36-43, 2001.
  19. McCullers, JA, Vargas, SL, Flynn, PM, Razzouk, BI, Shenep, JL. Candidal meningitis in children with cancer. Clin Infect Dis, 31 (2), 451-7, 2000.
  20. Rodman, JH, Flynn, PM, Robbins, B, Jimenez, E, Bardeguez, AD, Rodriguez, JF, Blanchard, S, Fridland, A. Systemic pharmacokinetics and cellular pharmacology of zidovudine in human immunodeficiency virus type 1-infected women and newborn infants. J Infect Dis, 180 (6), 1844-50, 1999.
  21. Abbasi, S, Shenep, JL, Hughes, WT, Flynn, PM. Aspergillosis in children with cancer: A 34-year experience. Clin Infect Dis, 29 (5), 1210-9, 1999.
  22. Schuetz, JD, Connelly, MC, Sun, D, Paibir, SG, Flynn, PM, Srinivas, RV, Kumar, A, Fridland, A. MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs. Nat Med, 5 (9), 1048-51, 1999.
  23. Caver, TE, Slobod, KS, Flynn, PM, Behm, FG, Hudson, MM, Turner, EV, Webster, RG, Boyett, JM, Tassie, TL, Pui, CH, Hurwitz, JL. Profound abnormality of the B/T lymphocyte ratio during chemotherapy for pediatric acute lymphoblastic leukemia. Leukemia, 12 (4), 619-22, 1998.
  24. McCullers, JA, Flynn, PM. Candida tropicalis osteomyelitis: case report and review. Clin Infect Dis, 26 (4), 1000-1, 1998.
  25. Choueiry, MA, Scurto, PL, Flynn, PM, Rao, BN, Hughes, WT. Disseminated infection due to Mycobacterium fortuitum in a patient with desmoid tumor. Clin Infect Dis, 26 (1), 237-8, 1998.
  26. Shenep, JL, Flynn, PM. Pulmonary fungal infections in immunocompromised children. Curr Opin Pediatr, 9 (3), 213-8, 1997.
  27. Sandlund, JT, Kauffman, W, Flynn, PM. Strongyloides stercoralis infection mimicking relapse in a child with small noncleaved cell lymphoma. Am J Clin Oncol, 20 (2), 215-6, 1997.
  28. Kaste, SC, Flynn, PM, Furman, WL. Acute lymphoblastic leukemia presenting with typhlitis. Med Pediatr Oncol, 28 (3), 209-12, 1997.
  29. Slobod, KS, Bennett, TA, Freiden, PJ, Kechli, AM, Howlett, N, Flynn, PM, Head, DR, Srivastava, DK, Boyett, JM, Brenner, MK, Garcia, JV. Mobilization of CD34+ progenitor cells by granulocyte colony-stimulating factor in human immunodeficiency virus type 1-infected adults. Blood, 88 (9), 3329-35, 1996.
  30. Rodman, JH, Robbins, B, Flynn, PM, Fridland, A. A systemic and cellular model for zidovudine plasma concentrations and intracellular phosphorylation in patients. J Infect Dis, 174 (3), 490-9, 1996.
  31. Flynn, PM. Emerging diarrheal pathogens: Cryptosporidium parvum, Isospora belli, Cyclospora species, and microsporidia. Pediatr Ann, 25 (9), 480-1, 485-7, 1996.
  32. Flynn, PM. Hepatitis C infections. Pediatr Ann, 25 (9), 496-500, 1996.
  33. Flynn, PM, Cunningham, CK, Kerkering, T, San Jorge, AR, Peters, VB, Pitel, PA, Harris, J, Gilbert, G, Castagnaro, L, Robinson, P. Oropharyngeal candidiasis in immunocompromised children: a randomized, multicenter study of orally administered fluconazole suspension versus nystatin. The Multicenter Fluconazole Study Group. J Pediatr, 127 (2), 322-8, 1995.
  34. Flynn, PM, Shenep, JL, Crawford, R, Hughes, WT. Use of abdominal computed tomography for identifying disseminated fungal infection in pediatric cancer patients. Clin Infect Dis, 20 (4), 964-70, 1995.
  35. Shenep, JL, Hughes, WT, Flynn, PM, Roberson, PK, Behm, FG, Fullen, GH, Kovnar, SG, Guito, KP, Brodkey, TO. Decreased counts of blood neutrophils, monocytes, and platelets in human immunodeficiency virus-infected children and young adults treated with diethyldithiocarbamate. Antimicrob Agents Chemother, 38 (7), 1644-6, 1994.
  36. Robbins, BL, Rodman, J, McDonald, C, Srinivas, RV, Flynn, PM, Fridland, A. Enzymatic assay for measurement of zidovudine triphosphate in peripheral blood mononuclear cells. Antimicrob Agents Chemother, 38 (1), 115-21, 1994.
  37. Flynn, PM. Pediatric HIV infection and the primary care physician. Meeting unique needs. Postgrad Med, 95 (1), 59-60, 65-8, 72-4, 1994.
  38. Sloas, MM, Flynn, PM, Kaste, SC, Patrick, CC. Typhlitis in children with cancer: a 30-year experience. Clin Infect Dis, 17 (3), 484-90, 1993.
  39. Wilimas, JA, Flynn, PM, Harris, S, Day, SW, Smith, R, Chesney, PJ, Rodman, JH, Eguiguren, JM, Fairclough, DL, Wang, WC. A randomized study of outpatient treatment with ceftriaxone for selected febrile children with sickle cell disease. N Engl J Med, 329 (7), 472-6, 1993.
  40. Vargas, SL, Shenep, JL, Flynn, PM, Pui, CH, Santana, VM, Hughes, WT. Azithromycin for treatment of severe Cryptosporidium diarrhea in two children with cancer. J Pediatr, 123 (1), 154-6, 1993.
  41. Flynn, PM, Marina, NM, Rivera, GK, Hughes, WT. Candida tropicalis infections in children with leukemia. Leuk Lymphoma, 10 (4-5), 369-76, 1993.
  42. Brint, JM, Flynn, PM, Pearson, TA, Pui, CH. Disseminated fusariosis involving bone in an adolescent with leukemia. Pediatr Infect Dis J, 11 (11), 965-8, 1992.
  43. Patrick, CC, Flynn, PM, Henwick, S, Pui, CH. Disseminated histoplasmosis presenting as a cystic duct obstruction. Pediatr Infect Dis J, 11 (7), 593-4, 1992.
  44. Marina, NM, Flynn, PM, Rivera, GK, Hughes, WT. Candida tropicalis and Candida albicans fungemia in children with leukemia. Cancer, 68 (3), 594-9, 1991.
  45. Shenep, JL, Adair, JR, Hughes, WT, Roberson, PK, Flynn, PM, Brodkey, TO, Fullen, GH, Kennedy, WT, Oakes, LL, Marina, NM. Infrared, thermistor, and glass-mercury thermometry for measurement of body temperature in children with cancer. Clin Pediatr (Phila), 30 (4 Suppl), 36-41; discussion 49, 1991.
  46. Hughes, WT, Kennedy, W, Shenep, JL, Flynn, PM, Hetherington, SV, Fullen, G, Lancaster, DJ, Stein, DS, Palte, S, Rosenbaum, D. Safety and pharmacokinetics of 566C80, a hydroxynaphthoquinone with anti-Pneumocystis carinii activity: a phase I study in human immunodeficiency virus (HIV)-infected men. J Infect Dis, 163 (4), 843-8, 1991.
  47. Flynn, PM, Magill, HL, Jenkins, JJ, Pearson, T, Crist, WM, Hughes, WT. Aspergillus osteomyelitis in a child treated for acute lymphoblastic leukemia. Pediatr Infect Dis J, 9 (10), 733-6, 1990.
  48. Henrickson, KJ, Shenep, JL, Flynn, PM, Pui, CH. Primary cutaneous bacillus cereus infection in neutropenic children. Lancet, 1 (8638), 601-3, 1989.
  49. Flynn, PM, Shenep, JL, Gigliotti, F, Davis, DS, Hildner, WK. Immunolabeling of lipopolysaccharide liberated from antibiotic-treated Escherichia coli. Infect Immun, 56 (10), 2760-2, 1988.
  50. Flynn, PM, Van Hooser, B, Gigliotti, F. Atypical mycobacterial infections of Hickman catheter exit sites. Pediatr Infect Dis J, 7 (7), 510-3, 1988.
  51. Flynn, PM, Shenep, JL, Barrett, FF. Differential quantitation with a commercial blood culture tube for diagnosis of catheter-related infection. J Clin Microbiol, 26 (5), 1045-6, 1988.
  52. Shenep, JL, Flynn, PM, Barrett, FF, Stidham, GL, Westenkirchner, DF. Serial quantitation of endotoxemia and bacteremia during therapy for gram-negative bacterial sepsis. J Infect Dis, 157 (3), 565-8, 1988.
  53. Flynn, PM, Shenep, JL, Stokes, DC, Fairclough, D, Hildner, WK. Polymyxin B moderates acidosis and hypotension in established, experimental gram-negative septicemia. J Infect Dis, 156 (5), 706-12, 1987.
  54. Flynn, PM, Shenep, JL, Stokes, DC, Barrett, FF. In situ management of confirmed central venous catheter-related bacteremia. Pediatr Infect Dis J, 6 (8), 729-34, 1987.