LINDA K. MYERS, M.D., B.A.

Professor
Pediatrics-Imm/Rheu

Office: 301 LE BONHEUR RESEARCH CENTER
50 NORTH DUNLAP STREET
MEMPHIS TN 381032893
Tel: (901) 448-5774
lmyers@uthsc.edu

Publications

  1. Brown, ML, Chesney, PJ, Ault, BH, Delos Santos, NM, Truong, LD, Lohr, KM, Myers, LK. Fever and rash. Clin Pediatr (Phila), 47 (6), 610-4, 2008.
  2. Myers, LK, Tang, B, Rosioniec, EF, Stuart, JM, Kang, AH. An altered peptide ligand of type II collagen suppresses autoimmune arthritis. Crit Rev Immunol, 27 (4), 345-56, 2008.
  3. Ye, XJ, Tang, B, Ma, Z, Zhou, J, Myers, LK, Kang, AH, Cremer, MA. The effects of interleukin-18 on rat articular chondrocytes: a study of mRNA expression and protein synthesis of proinflammatory substances. Clin Exp Immunol, 149 (3), 553-60, 2007.
  4. Myers, LK, Bhattacharya, SD, Herring, PA, Xing, Z, Goorha, S, Smith, RA, Bhattacharya, SK, Carbone, L, Faccio, R, Kang, AH, Ballou, LR. The isozyme-specific effects of cyclooxygenase-deficiency on bone in mice. Bone, 39 (5), 1048-52, 2006.
  5. Sakurai, Y, Brand, DD, Tang, B, Rosloniec, EF, Stuart, JM, Kang, AH, Myers, LK. Analog peptides of type II collagen can suppress arthritis in HLA-DR4 (DRB1*0401) transgenic mice. Arthritis Res Ther, 8 (5), R150, 2006.
  6. Head, AJ, Myers, LK, Watsky, MA, Greenwell, MW, Barrow, KD, Michelson, JA, Carbone, LD. Bone mineral density and turnover in non-corticosteroid treated African American children with juvenile rheumatoid arthritis. J Rheumatol, 33 (5), 1001-3, 2006.
  7. Sakurai, Y, Tang, B, Rosloniec, EF, Stuart, JM, Kang, AH, Myers, LK. Molecular characterization of an arthritogenic collagen peptide interacting with I-Ar. Immunology, 117 (1), 136-42, 2006.
  8. Chhokar, VS, Sun, Y, Bhattacharya, SK, Ahokas, RA, Myers, LK, Xing, Z, Smith, RA, Gerling, IC, Weber, KT. Hyperparathyroidism and the calcium paradox of aldosteronism. Circulation, 111 (7), 871-8, 2005.
  9. Head, AJ, Myers, LK, Thompson, JD, Buckingham, SC, Skinner, RB. Disseminated blastomycosis presenting as oligoarticular septic arthritis in a 12-year-old girl. Arthritis Rheum, 53 (1), 138-41, 2005.
  10. Chhokar, VS, Sun, Y, Bhattacharya, SK, Ahokas, RA, Myers, LK, Xing, Z, Smith, RA, Gerling, IC, Weber, KT. Loss of bone minerals and strength in rats with aldosteronism. Am J Physiol Heart Circ Physiol, 287 (5), H2023-6, 2004.
  11. Tang, B, Brand, DD, Ma, Z, Stuart, JM, Myers, LK, Kang, AH. Pathogenesis of collagen-induced arthritis: modulation of disease by arthritogenic T-cell epitope location. Immunology, 113 (3), 384-91, 2004.
  12. Myers, LK, Tang, B, Brand, DD, Rosloniec, EF, Stuart, JM, Kang, AH. Efficacy of modified recombinant type II collagen in modulating autoimmune arthritis. Arthritis Rheum, 50 (9), 3004-11, 2004.
  13. Cremer, MA, Ye, XJ, Myers, LK, Brand, DD, Rosloniec, EF, Kang, AH. T cell immunity to type II collagen in the biobreeding rat: the identification and characterization of RT1u-restricted T cell epitopes on alpha 1(II). J Immunol, 173 (3), 1795-801, 2004.
  14. Ye, XJ, Tang, B, Ma, Z, Kang, AH, Myers, LK, Cremer, MA. The roles of interleukin-18 in collagen-induced arthritis in the BB rat. Clin Exp Immunol, 136 (3), 440-7, 2004.
  15. He, X, Rosloniec, EF, Myers, LK, McColgan, WL, Gumanovskaya, M, Kang, AH, Stuart, JM. T cell receptors recognizing type II collagen in HLA-DR-transgenic mice characterized by highly restricted V beta usage. Arthritis Rheum, 50 (6), 1996-2004, 2004.
  16. Myers, LK, Sakurai, Y, Rosloniec, EF, Stuart, JM, Kang, AH. An analog peptide that suppresses collagen-induced arthritis. Am J Med Sci, 327 (4), 212-6, 2004.
  17. Myers, LK, Myllyharju, J, Nokelainen, M, Brand, DD, Cremer, MA, Stuart, JM, Bodo, M, Kivirikko, KI, Kang, AH. Relevance of posttranslational modifications for the arthritogenicity of type II collagen. J Immunol, 172 (5), 2970-5, 2004.
  18. Myers, LK, Sakurai, Y, Tang, B, He, X, Rosloniec, EF, Stuart, JM, Kang, AH. Peptide-induced suppression of collagen-induced arthritis in HLA-DR1 transgenic mice. Arthritis Rheum, 46 (12), 3369-77, 2002.
  19. Navarro, MJ, Higgins, GC, Lohr, KM, Myers, LK. Amelioration of relapsing polychondritis in a child treated with oral collagen. Am J Med Sci, 324 (2), 101-3, 2002.
  20. Myers, LK, Pihlajamaa, T, Brand, DD, Cremer, MA, Bodo, M, Ala-Kokko, L, Kang, AH. Immunogenicity of recombinant type IX collagen in murine collagen-induced arthritis. Arthritis Rheum, 46 (4), 1086-93, 2002.
  21. Myers, LK, Tang, B, Stuart, JM, Kang, AH. The role of IL-4 in regulation of murine collagen-induced arthritis. Clin Immunol, 102 (2), 185-91, 2002.
  22. Brand, DD, Myers, LK, Whittington, KB, Latham, KA, Stuart, JM, Kang, AH, Rosloniec, EF. Detection of early changes in autoimmune T cell phenotype and function following intravenous administration of type II collagen in a TCR-transgenic model. J Immunol, 168 (1), 490-8, 2002.
  23. Kang, ES, Cates, TB, Harper, DN, Chiang, TM, Myers, LK, Acchiardo, SR, Kimoto, M. An enzyme hydrolyzing methylated inhibitors of nitric oxide synthase is present in circulating human red blood cells. Free Radic Res, 35 (6), 693-707, 2001.
  24. Myers, LK, Higgins, GC, Finkel, TH, Reed, AM, Thompson, JW, Walton, RC, Hendrickson, J, Kerr, NC, Pandya-Lipman, RK, Shlopov, BV, Stastny, P, Postlethwaite, AE, Kang, AH. Juvenile arthritis and autoimmunity to type II collagen. Arthritis Rheum, 44 (8), 1775-81, 2001.
  25. Rosloniec, EF, Cremer, M, Kang, A, Myers, LK. Collagen-induced arthritis. Curr Protoc Immunol, Chapter 15, Unit 15.5, 2001.
  26. Myers, LK, Kang, AH, Postlethwaite, AE, Rosloniec, EF, Morham, SG, Shlopov, BV, Goorha, S, Ballou, LR. The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis. Arthritis Rheum, 43 (12), 2687-93, 2000.
  27. Sangster, MY, Topham, DJ, D'Costa, S, Cardin, RD, Marion, TN, Myers, LK, Doherty, PC. Analysis of the virus-specific and nonspecific B cell response to a persistent B-lymphotropic gammaherpesvirus. J Immunol, 164 (4), 1820-8, 2000.
  28. Tang, B, Brand, DD, Chiang, TM, Stuart, JM, Kang, AH, Myers, LK. Immunogenicity and arthritogenicity of recombinant CB10 in B10.RIII mice. J Immunol, 164 (1), 481-7, 2000.
  29. Tang, B, Chiang, TM, Brand, DD, Gumanovskaya, ML, Stuart, JM, Kang, AH, Myers, LK. Molecular definition and characterization of recombinant bovine CB8 and CB10: immunogenicity and arthritogenicity. Clin Immunol, 92 (3), 256-64, 1999.
  30. Gumanovskaya, ML, Myers, LK, Rosloniec, EF, Stuart, JM, Kang, AH. Intravenous tolerization with type II collagen induces interleukin-4-and interleukin-10-producing CD4+ T cells. Immunology, 97 (3), 466-73, 1999.
  31. McKown, KM, Carbone, LD, Kaplan, SB, Aelion, JA, Lohr, KM, Cremer, MA, Bustillo, J, Gonzalez, M, Kaeley, G, Steere, EL, Somes, GW, Myers, LK, Seyer, JM, Kang, AH, Postlethwaite, AE. Lack of efficacy of oral bovine type II collagen added to existing therapy in rheumatoid arthritis. Arthritis Rheum, 42 (6), 1204-8, 1999.
  32. Lew, DB, Higgins, GC, Skinner, RB, Snider, MD, Myers, LK. Adverse reaction to prednisone in a patient with systemic lupus erythematosus. Pediatr Dermatol, 16 (2), 146-50, 1999.
  33. Kang, ES, Tevlin, MT, Wang, YB, Chiang, TM, Cardenas, R, Myers, LK, Acchiardo, SR. Hemodialysis hypotension: interaction of inhibitors, iNOS, and the interdialytic period. Am J Med Sci, 317 (1), 9-21, 1999.
  34. Myers, LK, Brand, DD, Ye, XJ, Cremer, MA, Rosloniec, EF, Bodo, M, Myllyharju, J, Helaakoski, T, Nokelainen, M, Pihlajaniemi, T, Kivirikko, K, Yang, CL, Ala-Kokko, L, Prockop, DJ, Notbohm, H, Fietzek, P, Stuart, JM, Kang, AH. Characterization of recombinant type II collagen: arthritogenicity and tolerogenicity in DBA/1 mice. Immunology, 95 (4), 631-9, 1998.
  35. Myers, LK, Tang, B, Rosloniec, EF, Stuart, JM, Chiang, TM, Kang, AH. Characterization of a peptide analog of a determinant of type II collagen that suppresses collagen-induced arthritis. J Immunol, 161 (7), 3589-95, 1998.
  36. Tang, B, Myers, LK, Rosloniec, EF, Whittington, KB, Stuart, JM, Kang, AH. Characterization of signal transduction through the TCR-zeta chain following T cell stimulation with analogue peptides of type II collagen 260-267. J Immunol, 160 (7), 3135-42, 1998.
  37. Kawamura, S, Miyahara, H, Esaki, Y, Myers, LK, Rosloniec, EF, Stuart, JM, Kang, AH. Restricted TCR V alpha repertoire in the T cell response to a tolerogenic determinant of type II collagen. J Immunol, 158 (12), 6013-8, 1997.
  38. Myers, LK, Seyer, JM, Stuart, JM, Kang, AH. Suppression of murine collagen-induced arthritis by nasal administration of collagen. Immunology, 90 (2), 161-4, 1997.
  39. Myers, LK, Rosloniec, EF, Cremer, MA, Kang, AH. Collagen-induced arthritis, an animal model of autoimmunity. Life Sci, 61 (19), 1861-78, 1997.
  40. Brand, DD, Marion, TN, Myers, LK, Rosloniec, EF, Watson, WC, Stuart, JM, Kang, AH. Autoantibodies to murine type II collagen in collagen-induced arthritis: a comparison of susceptible and nonsusceptible strains. J Immunol, 157 (11), 5178-84, 1996.
  41. Rosloniec, EF, Whittington, KB, Brand, DD, Myers, LK, Stuart, JM. Identification of MHC class II and TCR binding residues in the type II collagen immunodominant determinant mediating collagen-induced arthritis. Cell Immunol, 172 (1), 21-8, 1996.
  42. Kang-Rotondo, CH, Major, S, Chiang, TM, Myers, LK, Kang, ES. Upregulation of nitric oxide synthase in cultured human keratinocytes after ultraviolet B and bradykinin. Photodermatol Photoimmunol Photomed, 12 (2), 57-65, 1996.
  43. Miyahara, H, Myers, LK, Rosloniec, EF, Brand, DD, Seyer, JM, Stuart, JM, Kang, AH. Identification and characterization of a major tolerogenic T-cell epitope of type II collagen that suppresses arthritis in B10.RIII mice. Immunology, 86 (1), 110-5, 1995.
  44. Myers, LK, Miyahara, H, Terato, K, Seyer, JM, Stuart, JM, Kang, AH. Collagen-induced arthritis in B10.RIII mice (H-2r): identification of an arthritogenic T-cell determinant. Immunology, 84 (4), 509-13, 1995.
  45. Myers, LK, Cooper, SW, Terato, K, Seyer, JM, Stuart, JM, Kang, AH. Identification and characterization of a tolerogenic T cell determinant within residues 181-209 of chick type II collagen. Clin Immunol Immunopathol, 75 (1), 33-8, 1995.
  46. Brand, DD, Myers, LK, Terato, K, Whittington, KB, Stuart, JM, Kang, AH, Rosloniec, EF. Characterization of the T cell determinants in the induction of autoimmune arthritis by bovine alpha 1(II)-CB11 in H-2q mice. J Immunol, 152 (6), 3088-97, 1994.
  47. Kang, ES, Betts, D, Fain, JN, Bahouth, SW, Myers, LK. Chronic exposure of rat fat cells to insulin enhances lipolysis and activation of partially purified hormone-sensitive lipase. Diabetes, 42 (10), 1415-24, 1993.
  48. Myers, LK, Seyer, JM, Stuart, JM, Terato, K, David, CS, Kang, AH. T cell epitopes of type II collagen that regulate murine collagen-induced arthritis. J Immunol, 151 (1), 500-5, 1993.
  49. Myers, LK, Rosloniec, EF, Seyer, JM, Stuart, JM, Kang, AH. A synthetic peptide analogue of a determinant of type II collagen prevents the onset of collagen-induced arthritis. J Immunol, 150 (10), 4652-8, 1993.
  50. Myers, LK, Terato, K, Seyer, JM, Stuart, JM, Kang, AH. Characterization of a tolerogenic T cell epitope of type II collagen and its relevance to collagen-induced arthritis. J Immunol, 149 (4), 1439-43, 1992.
  51. Kang, ES, Lee, HJ, Boulet, J, Myers, LK, Cook, GA, Bean, W. Potential for hepatic and renal dysfunction during influenza B infection, convalescence, and after induction of secondary viremia. J Exp Pathol, 6 (1-2), 133-44, 1992.
  52. Leggiadro, RJ, Birnbaum, SE, Chase, NA, Myers, LK. A resurgence of acute rheumatic fever in a mid-South children's hospital. South Med J, 83 (12), 1418-20, 1990.
  53. Myers, LK, Kang, ES. Modulation of natural killer cell activity by surface phosphorylation reactions. Exp Cell Res, 187 (2), 270-6, 1990.
  54. Myers, LK, Stuart, JM, Seyer, JM, Kang, AH. Identification of an immunosuppressive epitope of type II collagen that confers protection against collagen-induced arthritis. J Exp Med, 170 (6), 1999-2010, 1989.
  55. Myers, LK, Stuart, JM, Kang, AH. A CD4 cell is capable of transferring suppression of collagen-induced arthritis. J Immunol, 143 (12), 3976-80, 1989.