Associate Professor

MEMPHIS TN 381632243
Tel: (901) 448-1715


  1. Zhang, J, Kundu, M, Ney, PA. Mitophagy in mammalian cells: the reticulocyte model. Methods Enzymol, 452, 227-45, 2009.
  2. Zhang, J, Ney, PA. Role of BNIP3 and NIX in cell death, autophagy, and mitophagy. Cell Death Differ, 2009.
  3. Lu, Y, Zhang, X, Beheshti, B, Zhang, J. Adenoviral-mediated pHyde gene transfer and cisplatin additively inhibit human prostate cancer growth by enhancing apoptosis. Prostate, 69 (3), 234-48, 2009.
  4. Mullighan, CG, Su, X, Zhang, J, Radtke, I, Phillips, LA, Miller, CB, Ma, J, Liu, W, Cheng, C, Schulman, BA, Harvey, RC, Chen, IM, Clifford, RJ, Carroll, WL, Reaman, G, Bowman, WP, Devidas, M, Gerhard, DS, Yang, W, Relling, MV, Shurtleff, SA, Campana, D, Borowitz, MJ, Pui, CH, Smith, M, Hunger, SP, Willman, CL, Downing, JR, ,. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med, 360 (5), 470-80, 2009.
  5. Chow, LM, Zhang, J, Baker, SJ. Inducible Cre recombinase activity in mouse mature astrocytes and adult neural precursor cells. Transgenic Res, 17 (5), 919-28, 2008.
  6. Zhang, J, Lu, A, Beech, D, Jiang, B, Lu, Y. Suppression of breast cancer metastasis through the inhibition of VEGF-mediated tumor angiogenesis. Cancer Ther, 5, 273-286, 2008.
  7. Zhang, J, Ney, PA. NIX induces mitochondrial autophagy in reticulocytes. Autophagy, 4 (3), 354-6, 2008.
  8. Martins, RA, Zindy, F, Donovan, S, Zhang, J, Pounds, S, Wey, A, Knoepfler, PS, Eisenman, RN, Roussel, MF, Dyer, MA. N-myc coordinates retinal growth with eye size during mouse development. Genes Dev, 22 (2), 179-93, 2008.
  9. Schweers, RL, Zhang, J, Randall, MS, Loyd, MR, Li, W, Dorsey, FC, Kundu, M, Opferman, JT, Cleveland, JL, Miller, JL, Ney, PA. NIX is required for programmed mitochondrial clearance during reticulocyte maturation. Proc Natl Acad Sci U S A, 104 (49), 19500-5, 2007.
  10. Houghton, PJ, Morton, CL, Tucker, C, Payne, D, Favours, E, Cole, C, Gorlick, R, Kolb, EA, Zhang, W, Lock, R, Carol, H, Tajbakhsh, M, Reynolds, CP, Maris, JM, Courtright, J, Keir, ST, Friedman, HS, Stopford, C, Zeidner, J, Wu, J, Liu, T, Billups, CA, Khan, J, Ansher, S, Zhang, J, Smith, MA. The pediatric preclinical testing program: description of models and early testing results. Pediatr Blood Cancer, 49 (7), 928-40, 2007.
  11. Xu, KM, Smith, GJ, Bahl, J, Duan, L, Tai, H, Vijaykrishna, D, Wang, J, Zhang, JX, Li, KS, Fan, XH, Webster, RG, Chen, H, Peiris, JS, Guan, Y. The genesis and evolution of H9N2 influenza viruses in poultry from southern China, 2000 to 2005. J Virol, 81 (19), 10389-401, 2007.
  12. Shanklin, DR, Zhang, J. Neonate with a single umbilical vessel: a case report. J Reprod Med, 52 (6), 529-32, 2007.
  13. Johnson, DA, Zhang, J, Frase, S, Wilson, M, Rodriguez-Galindo, C, Dyer, MA. Neuronal differentiation and synaptogenesis in retinoblastoma. Cancer Res, 67 (6), 2701-11, 2007.
  14. Laurie, NA, Donovan, SL, Shih, CS, Zhang, J, Mills, N, Fuller, C, Teunisse, A, Lam, S, Ramos, Y, Mohan, A, Johnson, D, Wilson, M, Rodriguez-Galindo, C, Quarto, M, Francoz, S, Mendrysa, SM, Guy, RK, Marine, JC, Jochemsen, AG, Dyer, MA. Inactivation of the p53 pathway in retinoblastoma. Nature, 444 (7115), 61-6, 2006.
  15. Denson, J, Xi, Z, Wu, Y, Yang, W, Neale, G, Zhang, J. Screening for inter-individual splicing differences in human GSTM4 and the discovery of a single nucleotide substitution related to the tandem skipping of two exons. Gene, 379, 148-55, 2006.
  16. Ganti, R, Skapek, SX, Zhang, J, Fuller, CE, Wu, J, Billups, CA, Breitfeld, PP, Dalton, JD, Meyer, WH, Khoury, JD. Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma. Mod Pathol, 19 (9), 1213-20, 2006.
  17. Zhang, Y, Ferreira, A, Cheng, C, Wu, Y, Zhang, J. Modeling oligonucleotide microarray signals. Appl Bioinformatics, 5 (3), 151-60, 2006.
  18. Zhang, J, Randall, MS, Loyd, MR, Li, W, Schweers, RL, Persons, DA, Rehg, JE, Noguchi, CT, Ihle, JN, Ney, PA. Role of erythropoietin receptor signaling in Friend virus-induced erythroblastosis and polycythemia. Blood, 107 (1), 73-8, 2006.
  19. Laurie, NA, Gray, JK, Zhang, J, Leggas, M, Relling, M, Egorin, M, Stewart, C, Dyer, MA. Topotecan combination chemotherapy in two new rodent models of retinoblastoma. Clin Cancer Res, 11 (20), 7569-78, 2005.
  20. Wu, Y, Zhang, Y, Zhang, J. Distribution of exonic splicing enhancer elements in human genes. Genomics, 86 (3), 329-36, 2005.
  21. Denson, J, Wu, Y, Yang, W, Zhang, J. Inter-individual variation of several cytochrome P450 2D6 splice variants in human liver. Biochem Biophys Res Commun, 330 (2), 498-504, 2005.
  22. Dyer, MA, Donovan, SL, Zhang, J, Gray, J, Ortiz, A, Tenney, R, Kong, J, Allikmets, R, Sohocki, MM. Retinal degeneration in Aipl1-deficient mice: a new genetic model of Leber congenital amaurosis. Brain Res Mol Brain Res, 132 (2), 208-20, 2004.
  23. Lu, L, Chen, SS, Zhang, JQ, Ramires, FJ, Sun, Y. Activation of nuclear factor-kappaB and its proinflammatory mediator cascade in the infarcted rat heart. Biochem Biophys Res Commun, 321 (4), 879-85, 2004.
  24. Zhang, J, Schweers, B, Dyer, MA. The first knockout mouse model of retinoblastoma. Cell Cycle, 3 (7), 952-9, 2004.
  25. Lu, L, Zhang, JQ, Ramires, FJ, Sun, Y. Molecular and cellular events at the site of myocardial infarction: from the perspective of rebuilding myocardial tissue. Biochem Biophys Res Commun, 320 (3), 907-13, 2004.
  26. Schuetz, EG, Relling, MV, Kishi, S, Yang, W, Das, S, Chen, P, Cook, EH, Rosner, GL, Pui, CH, Blanco, JG, Edick, MJ, Hancock, ML, Winick, NJ, Dervieux, T, Amylon, MD, Bash, RO, Behm, FG, Camitta, BM, Raimondi, SC, Goh, BC, Lee, SC, Wang, LZ, Fan, L, Guo, JY, Lamba, J, Lim, R, Lim, HL, Ong, AB, Lee, HS, Kuehl, P, Zhang, J, Lin, Y, Assem, M, Schuetz, J, Watkins, PB, Daly, A, Wrighton, SA, Hall, SD, Maurel, P, Brimer, C, Yasuda, K, Venkataramanan, R, Strom, S, Thummel, K, Boguski, MS. PharmGKB update: II. CYP3A5, cytochrome P450, family 3, subfamily A, polypeptide 5. Pharmacol Rev, 56 (2), 159, 2004.
  27. Zhang, J, Handorf, C. Miliary tuberculosis presenting as acute respiratory distress syndrome, septic shock, DIC, and multiorgan failure. Tenn Med, 97 (4), 164-6, 2004.
  28. Zhang, J, Gray, J, Wu, L, Leone, G, Rowan, S, Cepko, CL, Zhu, X, Craft, CM, Dyer, MA. Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nat Genet, 36 (4), 351-60, 2004.
  29. Sun, Y, Zhang, J, Lu, L, Bedigian, MP, Robinson, AD, Weber, KT. Tissue angiotensin II in the regulation of inflammatory and fibrogenic components of repair in the rat heart. J Lab Clin Med, 143 (1), 41-51, 2004.
  30. Kwon, CH, Zhu, X, Zhang, J, Baker, SJ. mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo. Proc Natl Acad Sci U S A, 100 (22), 12923-8, 2003.
  31. Sun, Y, Zhang, J, Lu, L, Chen, SS, Quinn, MT, Weber, KT. Aldosterone-induced inflammation in the rat heart : role of oxidative stress. Am J Pathol, 161 (5), 1773-81, 2002.
  32. Lamba, JK, Lin, YS, Thummel, K, Daly, A, Watkins, PB, Strom, S, Zhang, J, Schuetz, EG. Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. Pharmacogenetics, 12 (2), 121-32, 2002.
  33. Zhang, J, Goorha, S, Raghow, R, Ballou, LR. The tissue-specific, compensatory expression of cyclooxygenase-1 and -2 in transgenic mice. Prostaglandins Other Lipid Mediat, 67 (2), 121-35, 2002.
  34. Kwon, CH, Zhu, X, Zhang, J, Knoop, LL, Tharp, R, Smeyne, RJ, Eberhart, CG, Burger, PC, Baker, SJ. Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease. Nat Genet, 29 (4), 404-11, 2001.
  35. Sun, Y, Zhang, J, Zhang, JQ, Weber, KT. Renin expression at sites of repair in the infarcted rat heart. J Mol Cell Cardiol, 33 (5), 995-1003, 2001.
  36. Zhang, JR, Mostov, KE, Lamm, ME, Nanno, M, Shimida, S, Ohwaki, M, Tuomanen, E. The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells. Cell, 102 (6), 827-37, 2000.
  37. Ballou, LR, Botting, RM, Goorha, S, Zhang, J, Vane, JR. Nociception in cyclooxygenase isozyme-deficient mice. Proc Natl Acad Sci U S A, 97 (18), 10272-6, 2000.
  38. Sun, Y, Zhang, J, Zhang, JQ, Ramires, FJ. Local angiotensin II and transforming growth factor-beta1 in renal fibrosis of rats. Hypertension, 35 (5), 1078-84, 2000.
  39. Zhang, JR, Tuomanen, E. Molecular and cellular mechanisms for microbial entry into the CNS. J Neurovirol, 5 (6), 591-603, 1999.
  40. Jaishankar, S, Zhang, J, Roussel, MF, Baker, SJ. Transforming activity of EWS/FLI is not strictly dependent upon DNA-binding activity. Oncogene, 18 (40), 5592-7, 1999.
  41. Zhang, JR, Idanpaan-Heikkila, I, Fischer, W, Tuomanen, EI. Pneumococcal licD2 gene is involved in phosphorylcholine metabolism. Mol Microbiol, 31 (5), 1477-88, 1999.
  42. Zhang, J, Obál, F, Zheng, T, Fang, J, Taishi, P, Krueger, JM. Intrapreoptic microinjection of GHRH or its antagonist alters sleep in rats. J Neurosci, 19 (6), 2187-94, 1999.
  43. Zhang, J, Chen, Z, Taishi, P, Obál, F, Fang, J, Krueger, JM. Sleep deprivation increases rat hypothalamic growth hormone-releasing hormone mRNA. Am J Physiol, 275 (6 Pt 2), R1755-61, 1998.
  44. Fernandes, ER, Zhang, JY, Rooney, RJ. Adenovirus E1A-regulated transcription factor p120E4F inhibits cell growth and induces the stabilization of the cdk inhibitor p21WAF1. Mol Cell Biol, 18 (1), 459-67, 1998.
  45. Zhang, J, Obál, F, Fang, J, Collins, BJ, Krueger, JM. Non-rapid eye movement sleep is suppressed in transgenic mice with a deficiency in the somatotropic system. Neurosci Lett, 220 (2), 97-100, 1996.
  46. Tan, WY, Zhang, JH. Monte Carlo results for the 3-poly test for animal carcinogenicity experiments. Environ Health Perspect, 104 (8), 872-7, 1996.
  47. Lessman, CA, Zhang, J, MacRae, TH. Posttranslational modifications and assembly characteristics of goldfish tubulin. Biol Cell, 79 (1), 63-70, 1993.