Andrzej Slominski, M.D., Ph.D.

Professor of Pathology
Director of Dermatopathology Fellowship Program
Director of the Skin Cancer Division of the UT Center for Cancer Research
Secretary-Treasurer of the Pan-American Society for Pigment Cell Research
Member of the Editorial Board of Experimental Dermatology
Member of the Editorial Board of Journal of Pineal Research

Office: 519 930 Madison Building
Tel: (901) 448-3741
aslominski@uthsc.edu
https://academic.uthsc.edu/faculty/Andrzej_Slominski.html

Education

  • Board Cert., Albany Medical Center, Albany, New York, USA, Dermapathology
  • Board Cert., Albany Medical Center, Albany, New York, USA, Anatomic Pathology
  • PostDoc, Yale University, School of Medicine, Department of Dermatology
  • Ph.D., School of Medicine, University of Gdansk, Poland, Tumor Biology
  • M.D., School of Medicine, Univeristy of Gdansk, Poland, Medicine

Clinical Care Specialty/Interest

Dr. Andrzej Slominski, MD, PhD, board certified in anatomic pathology and dermatopathology, serves as a dermatopathologist at the University of Tennessee, HSC. In addition, to general skin pathology his interest include atypical pigmented lesions and melanoma, skin cancer and inflammatory skin diseases

Related Links:

 http://www.uthsc.edu/pathology/

Publications

  1. Slominski, AT, Zmijewski, MA, Zbytek, B, Brozyna, AA, Granese, J, Pisarchik, A, Szczesniewski, A, Tobin, DJ. Regulated proenkephalin expression in human skin and cultured skin cells. J Invest Dermatol, 131 (3), 613-22, 2011.
  2. Slominski, AT, Kim, TK, Janjetovic, Z, Tuckey, RC, Bieniek, R, Yue, J, Li, W, Chen, J, Nguyen, MN, Tang, EK, Miller, D, Chen, TC, Holick, M. 20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells. Am J Physiol Cell Physiol, 300 (3), C526-41, 2011.
  3. Li, W, Chen, J, Janjetovic, Z, Kim, TK, Sweatman, T, Lu, Y, Zjawiony, J, Tuckey, RC, Miller, D, Slominski, A. Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity. Steroids, 75 (12), 926-35, 2010.
  4. Janjetovic, Z, Tuckey, RC, Nguyen, MN, Thorpe, EM, Slominski, AT. 20,23-dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF-kappaB activity in human keratinocytes. J Cell Physiol, 223 (1), 36-48, 2010.
  5. Kim, TK, Chen, J, Li, W, Zjawiony, J, Miller, D, Janjetovic, Z, Tuckey, RC, Slominski, A. A new steroidal 5,7-diene derivative, 3beta-hydroxyandrosta-5,7-diene-17beta-carboxylic acid, shows potent anti-proliferative activity. Steroids, 75 (3), 230-9, 2010.
  6. Yang, CH, Fan, M, Slominski, AT, Yue, J, Pfeffer, LM. The role of constitutively activated STAT3 in B16 melanoma cells. Int J Infereron Cytokine Mediator Res, 2010 (2), 1-7, 2010.
  7. Slominski, AT, Janjetovic, Z, Fuller, BE, Zmijewski, MA, Tuckey, RC, Nguyen, MN, Sweatman, T, Li, W, Zjawiony, J, Miller, D, Chen, TC, Lozanski, G, Holick, MF. Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity. PLoS One, 5 (3), e9907, 2009.
  8. Slominski, A. Neuroendocrine activity of the melanocyte. Exp Dermatol, 18 (9), 760-3, 2009.
  9. Slominski, A, Zbytek, B, Slominski, R. Inhibitors of melanogenesis increase toxicity of cyclophosphamide and lymphocytes against melanoma cells. Int J Cancer, 124 (6), 1470-7, 2009.
  10. Janjetovic, Z, Zmijewski, MA, Tuckey, RC, DeLeon, DA, Nguyen, MN, Pfeffer, LM, Slominski, AT. 20-Hydroxycholecalciferol, product of vitamin D3 hydroxylation by P450scc, decreases NF-kappaB activity by increasing IkappaB alpha levels in human keratinocytes. PLoS One, 4 (6), e5988, 2009.
  11. Li, W, Slominski, R, Slominski, AT. High-resolution magic angle spinning nuclear magnetic resonance analysis of metabolic changes in melanoma cells after induction of melanogenesis. Anal Biochem, 386 (2), 282-4, 2009.
  12. Zmijewski, MA, Li, W, Zjawiony, JK, Sweatman, TW, Chen, J, Miller, DD, Slominski, AT. Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives. Photochem Photobiol Sci, 7 (12), 1570-6, 2008.
  13. Slominski, AT, Zmijewski, MA, Semak, I, Sweatman, T, Janjetovic, Z, Li, W, Zjawiony, JK, Tuckey, RC. Sequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skin. PLoS ONE, 4 (2), e4309, 2008.
  14. Zmijewski, MA, Li, W, Zjawiony, JK, Sweatman, TW, Chen, J, Miller, DD, Slominski, AT. Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3beta, 17alpha, 20-triol and their bioactivity in melanoma cells. Steroids, 2008.
  15. Zmijewski, MA, Slominski, AT. CRF1 receptor splicing in epidermal keratinocytes: Potential biological role and environmental regulations. J Cell Physiol, 2008.
  16. Zbytek, B, Carlson, JA, Granese, J, Ross, J, Mihm, MC, Slominski, A. Current concepts of metastasis in melanoma. Expert Rev Dermatol, 3 (5), 569-585, 2008.
  17. Slominski, A, Wortsman, J, Paus, R, Elias, PM, Tobin, DJ, Feingold, KR. Skin as an endocrine organ: implications for its function. Drug Discov Today Dis Mech, 5 (2), 137-144, 2008.
  18. Zbytek, B, Janjetovic, Z, Tuckey, RC, Zmijewski, MA, Sweatman, TW, Jones, E, Nguyen, MN, Slominski, AT. 20-Hydroxyvitamin D3, a Product of Vitamin D3 Hydroxylation by Cytochrome P450scc, Stimulates Keratinocyte Differentiation. J Invest Dermatol, 2008.
  19. Brozyna AA, VanMiddlesworth L, Slominski AT.. Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy.. Int J Cancer (123), 1448-56, 2008.
  20. Slominski, A, Tobin, DJ, Zmijewski, MA, Wortsman, J, Paus, R. Melatonin in the skin: synthesis, metabolism and functions. Trends Endocrinol Metab, 19 (1), 17-24, 2008.
  21. Nordlind K, EC Azmitia, Slominski A. The skin as a mirror of the soul: Exploring the possible roles of serotonin. Exp Dermatol, 2008.
  22. Fischer, TW, Zmijewski, MA, Wortsman, J, Slominski, A. Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp-9) and effector caspases (casp-3/casp-7) and PARP in UVR-exposed HaCaT keratinocytes. J Pineal Res, 2007.
  23. Slominski, A. A nervous breakdown in the skin: stress and the epidermal barrier. J Clin Invest, 117 (11), 3166-9, 2007.
  24. Li, W, Wang, Z, Gududuru, V, Zbytek, B, Slominski, AT, Dalton, JT, Miller, DD. Structure-activity relationship studies of arylthiazolidine amides as selective cytotoxic agents for melanoma. Anticancer Res, 27 (2), 883-8, 2007.
  25. Zmijewski, MA, Sharma, RK, Slominski, AT. Expression of molecular equivalent of hypothalamic-pituitary-adrenal axis in adult retinal pigment epithelium. J Endocrinol, 193 (1), 157-69, 2007.
  26. Slominski, AT, Zmijewski, MA, Pisarchik, A, Wortsman, J. Molecular cloning and initial characterization of African green monkey (Cercopithecus aethiops) corticotropin releasing factor receptor type 1 (CRF1) from COS-7 cells. Gene, 389 (2), 154-62, 2007.
  27. Slominski, A, Wortsman, J, Tuckey, RC, Paus, R. Differential expression of HPA axis homolog in the skin. Mol Cell Endocrinol, 265-266, 143-9, 2007.
  28. Zbytek, B, Pfeffer, LM, Slominski, AT. CRH inhibits NF-kappa B signaling in human melanocytes. Peptides, 27 (12), 3276-83, 2006.
  29. Zbytek, B, Wortsman, J, Slominski, A. Characterization of a ultraviolet B-induced corticotropin-releasing hormone-proopiomelanocortin system in human melanocytes. Mol Endocrinol, 20 (10), 2539-47, 2006.
  30. Slominski, AT. Proopiomelanocortin signaling system is operating in mast cells. J Invest Dermatol, 126 (9), 1934-6, 2006.
  31. Fischer, TW, Zmijewski, MA, Zbytek, B, Sweatman, TW, Slominski, RM, Wortsman, J, Slominski, A. Oncostatic effects of the indole melatonin and expression of its cytosolic and nuclear receptors in cultured human melanoma cell lines. Int J Oncol, 29 (3), 665-72, 2006.
  32. Slominski, A, Semak, I, Wortsman, J, Zjawiony, J, Li, W, Zbytek, B, Tuckey, RC. An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2. FEBS J, 273 (13), 2891-901, 2006.
  33. Fischer, TW, Sweatman, TW, Semak, I, Sayre, RM, Wortsman, J, Slominski, A. Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems. FASEB J, 20 (9), 1564-6, 2006.
  34. Slominski, A, Zbytek, B, Zmijewski, M, Slominski, RM, Kauser, S, Wortsman, J, Tobin, DJ. Corticotropin releasing hormone and the skin. Front Biosci, 11, 2230-48, 2006.
  35. Slominski, A, Zbytek, B, Pisarchik, A, Slominski, RM, Zmijewski, MA, Wortsman, J. CRH functions as a growth factor/cytokine in the skin. J Cell Physiol, 206 (3), 780-91, 2006.
  36. Fischer, TW, Zbytek, B, Sayre, RM, Apostolov, EO, Basnakian, AG, Sweatman, TW, Wortsman, J, Elsner, P, Slominski, A. Melatonin increases survival of HaCaT keratinocytes by suppressing UV-induced apoptosis. J Pineal Res, 40 (1), 18-26, 2006.
  37. Slominski, A. Neuroendocrine system of the skin. Dermatology, 211 (3), 199-208, 2005.
  38. Slominski, A, Semak, I, Zjawiony, J, Wortsman, J, Gandy, MN, Li, J, Zbytek, B, Li, W, Tuckey, RC. Enzymatic metabolism of ergosterol by cytochrome p450scc to biologically active 17alpha,24-dihydroxyergosterol. Chem Biol, 12 (8), 931-9, 2005.
  39. Slominski, A, Semak, I, Zjawiony, J, Wortsman, J, Li, W, Szczesniewski, A, Tuckey, RC. The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism. FEBS J, 272 (16), 4080-90, 2005.
  40. Slominski, A, Fischer, TW, Zmijewski, MA, Wortsman, J, Semak, I, Zbytek, B, Slominski, RM, Tobin, DJ. On the role of melatonin in skin physiology and pathology. Endocrine, 27 (2), 137-48, 2005.
  41. Slominski, A, Zbytek, B, Semak, I, Sweatman, T, Wortsman, J. CRH stimulates POMC activity and corticosterone production in dermal fibroblasts. J Neuroimmunol, 162 (1-2), 97-102, 2005.
  42. Zbytek, B, Slominski, AT. Corticotropin-releasing hormone induces keratinocyte differentiation in the adult human epidermis. J Cell Physiol, 203 (1), 118-26, 2005.
  43. Slominski, A, Zbytek, B, Szczesniewski, A, Semak, I, Kaminski, J, Sweatman, T, Wortsman, J. CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH. Am J Physiol Endocrinol Metab, 288 (4), E701-6, 2005.
  44. Slominski, A, Plonka, PM, Pisarchik, A, Smart, JL, Tolle, V, Wortsman, J, Low, MJ. Preservation of eumelanin hair pigmentation in proopiomelanocortin-deficient mice on a nonagouti (a/a) genetic background. Endocrinology, 146 (3), 1245-53, 2005.
  45. Zbytek, B, Pikula, M, Slominski, RM, Mysliwski, A, Wei, E, Wortsman, J, Slominski, AT. Corticotropin-releasing hormone triggers differentiation in HaCaT keratinocytes. Br J Dermatol, 152 (3), 474-80, 2005.
  46. Slominski, A, Wortsman, J, Tobin, DJ. The cutaneous serotoninergic/melatoninergic system: securing a place under the sun. FASEB J, 19 (2), 176-94, 2005.
  47. Slominski, A, Wortsman, J, Plonka, PM, Schallreuter, KU, Paus, R, Tobin, DJ. Hair follicle pigmentation. J Invest Dermatol, 124 (1), 13-21, 2005.
  48. Slominski, A, Zjawiony, J, Wortsman, J, Semak, I, Stewart, J, Pisarchik, A, Sweatman, T, Marcos, J, Dunbar, C, C Tuckey, R. A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin. Eur J Biochem, 271 (21), 4178-88, 2004.
  49. Pisarchik, A, Wortsman, J, Slominski, A. A novel microarray to evaluate stress-related genes in skin: effect of ultraviolet light radiation. Gene, 341, 199-207, 2004.
  50. Slominski, A, Pisarchik, A, Wortsman, J. Expression of genes coding melatonin and serotonin receptors in rodent skin. Biochim Biophys Acta, 1680 (2), 67-70, 2004.
  51. Slominski, A, Tobin, DJ, Shibahara, S, Wortsman, J. Melanin pigmentation in mammalian skin and its hormonal regulation. Physiol Rev, 84 (4), 1155-228, 2004.
  52. Pisarchik, A, Slominski, A. Molecular and functional characterization of novel CRFR1 isoforms from the skin. Eur J Biochem, 271 (13), 2821-30, 2004.
  53. Zbytek, B, Pfeffer, LM, Slominski, AT. Corticotropin-releasing hormone stimulates NF-kappaB in human epidermal keratinocytes. J Endocrinol, 181 (3), R1-7, 2004.
  54. Slominski, A, Pisarchik, A, Tobin, DJ, Mazurkiewicz, JE, Wortsman, J. Differential expression of a cutaneous corticotropin-releasing hormone system. Endocrinology, 145 (2), 941-50, 2004.
  55. Carlson, JA, Slominski, A, Linette, GP, Mysliborski, J, Hill, J, Mihm, MC, Ross, JS. Malignant melanoma 2003: predisposition, diagnosis, prognosis, and staging. Am J Clin Pathol, 120 Suppl, S101-27, 2003.
  56. Zbytek, B, Pfeffer, LM, Slominski, AT. Corticotropin-releasing hormone inhibits nuclear factor-kappaB pathway in human HaCaT keratinocytes. J Invest Dermatol, 121 (6), 1496-9, 2003.
  57. Slominski, A, Pisarchik, A, Johansson, O, Jing, C, Semak, I, Slugocki, G, Wortsman, J. Tryptophan hydroxylase expression in human skin cells. Biochim Biophys Acta, 1639 (2), 80-6, 2003.
  58. Slominski, A, Pisarchik, A, Semak, I, Sweatman, T, Wortsman, J. Characterization of the serotoninergic system in the C57BL/6 mouse skin. Eur J Biochem, 270 (16), 3335-44, 2003.
  59. Slominski, A, Pisarchik, A, Zbytek, B, Tobin, DJ, Kauser, S, Wortsman, J. Functional activity of serotoninergic and melatoninergic systems expressed in the skin. J Cell Physiol, 196 (1), 144-53, 2003.
  60. Slominski, A, Wortsman, J. Self-regulated endocrine systems in the skin. Minerva Endocrinol, 28 (2), 135-43, 2003.
  61. Carlson, JA, Slominski, A, Linette, GP, Mihm, MC, Ross, JS. Biomarkers in melanoma: staging, prognosis and detection of early metastases. Expert Rev Mol Diagn, 3 (3), 303-30, 2003.
  62. Carlson, JA, Slominski, A, Linette, GP, Mihm, MC, Ross, JS. Biomarkers in melanoma: predisposition, screening and diagnosis. Expert Rev Mol Diagn, 3 (2), 163-84, 2003.
  63. Slominski, A, Wortsman, J, Kohn, L, Ain, KB, Venkataraman, GM, Pisarchik, A, Chung, JH, Giuliani, C, Thornton, M, Slugocki, G, Tobin, DJ. Expression of hypothalamic-pituitary-thyroid axis related genes in the human skin. J Invest Dermatol, 119 (6), 1449-55, 2002.
  64. Slominski, A, Pisarchik, A, Semak, I, Sweatman, T, Szczesniewski, A, Wortsman, J. Serotoninergic system in hamster skin. J Invest Dermatol, 119 (4), 934-42, 2002.
  65. Pisarchik, A, Slominski, A. Corticotropin releasing factor receptor type 1: molecular cloning and investigation of alternative splicing in the hamster skin. J Invest Dermatol, 118 (6), 1065-72, 2002.
  66. Slominski, A, Pisarchik, A, Semak, I, Sweatman, T, Wortsman, J, Szczesniewski, A, Slugocki, G, McNulty, J, Kauser, S, Tobin, DJ, Jing, C, Johansson, O. Serotoninergic and melatoninergic systems are fully expressed in human skin. FASEB J, 16 (8), 896-8, 2002.
  67. Carlson, JA, Grabowski, R, Mu, XC, Del Rosario, A, Malfetano, J, Slominski, A. Possible mechanisms of hypopigmentation in lichen sclerosus. Am J Dermatopathol, 24 (2), 97-107, 2002.
  68. Slominski, A, Wortsman, J, Foecking, MF, Shackleton, C, Gomez-Sanchez, C, Szczesniewski, A. Gas chromatography/mass spectrometry characterization of corticosteroid metabolism in human immortalized keratinocytes. J Invest Dermatol, 118 (2), 310-5, 2002.
  69. Slominski, A, Semak, I, Pisarchik, A, Sweatman, T, Szczesniewski, A, Wortsman, J. Conversion of L-tryptophan to serotonin and melatonin in human melanoma cells. FEBS Lett, 511 (1-3), 102-6, 2002.
  70. Zbytek, B, Mysliwski, A, Slominski, A, Wortsman, J, Wei, ET, Mysliwska, J. Corticotropin-releasing hormone affects cytokine production in human HaCaT keratinocytes. Life Sci, 70 (9), 1013-21, 2002.
  71. Carlson, JA, Mu, XC, Slominski, A, Weismann, K, Crowson, AN, Malfetano, J, Prieto, VG, Mihm, MC. Melanocytic proliferations associated with lichen sclerosus. Arch Dermatol, 138 (1), 77-87, 2002.
  72. Pisarchik, A, Slominski, AT. Alternative splicing of CRH-R1 receptors in human and mouse skin: identification of new variants and their differential expression. FASEB J, 15 (14), 2754-6, 2001.
  73. Slominski, A, Wortsman, J, Carlson, AJ, Matsuoka, LY, Balch, CM, Mihm, MC. Malignant melanoma. Arch Pathol Lab Med, 125 (10), 1295-306, 2001.
  74. Slominski, A, Wortsman, J, Pisarchik, A, Zbytek, B, Linton, EA, Mazurkiewicz, JE, Wei, ET. Cutaneous expression of corticotropin-releasing hormone (CRH), urocortin, and CRH receptors. FASEB J, 15 (10), 1678-93, 2001.
  75. Quevedo, ME, Slominski, A, Pinto, W, Wei, E, Wortsman, J. Pleiotropic effects of corticotropin releasing hormone on normal human skin keratinocytes. In Vitro Cell Dev Biol Anim, 37 (1), 50-4, 2001.
  76. Slominski, A, Malarkey, WB, Wortsman, J, Asa, SL, Carlson, A. Human skin expresses growth hormone but not the prolactin gene. J Lab Clin Med, 136 (6), 476-81, 2000.
  77. Slominski, A, Szczesniewski, A, Wortsman, J. Liquid chromatography-mass spectrometry detection of corticotropin-releasing hormone and proopiomelanocortin-derived peptides in human skin. J Clin Endocrinol Metab, 85 (10), 3582-8, 2000.
  78. Slominski, A, Wortsman, J. Neuroendocrinology of the skin. Endocr Rev, 21 (5), 457-87, 2000.
  79. Mazurkiewicz, JE, Corliss, D, Slominski, A. Spatiotemporal expression, distribution, and processing of POMC and POMC-derived peptides in murine skin. J Histochem Cytochem, 48 (7), 905-14, 2000.
  80. Slominski, A, Wortsman, J, Luger, T, Paus, R, Solomon, S. Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress. Physiol Rev, 80 (3), 979-1020, 2000.
  81. Slominski, A. Essential skin patholog. Arch Pathol Lab Med, 124 (4), 640, 2000.
  82. Slominski, AT, Roloff, B, Zbytek, B, Wei, ET, Fechner, K, Curry, J, Wortsman, J. Corticotropin releasing hormone and related peptides can act as bioregulatory factors in human keratinocytes. In Vitro Cell Dev Biol Anim, 36 (3), 211-6, 2000.
  83. Slominski, A, Gomez-Sanchez, CE, Foecking, MF, Wortsman, J. Active steroidogenesis in the normal rat skin. Biochim Biophys Acta, 1474 (1), 1-4, 2000.
  84. Slominski, A, Roloff, B, Curry, J, Dahiya, M, Szczesniewski, A, Wortsman, J. The skin produces urocortin. J Clin Endocrinol Metab, 85 (2), 815-23, 2000.
  85. Slominski, A, Wortsman, J, Carlson, A, Mihm, M, Nickoloff, B, McClatchey, K. Molecular pathology of soft tissue and bone tumors. A review. Arch Pathol Lab Med, 123 (12), 1246-59, 1999.
  86. Mazurkiewicz, JE, Corliss, D, Slominski, A. Differential temporal and spatial expression of POMC mRNA and of the production of POMC peptides during the murine hair cycle. Ann N Y Acad Sci, 885, 427-9, 1999.
  87. Slominski, A, Botchkareva, NV, Botchkarev, VA, Chakraborty, A, Luger, T, Uenalan, M, Paus, R. ACTH production in C57BL/6 mouse skin. Ann N Y Acad Sci, 885, 448-50, 1999.
  88. Slominski, AT, Botchkarev, V, Choudhry, M, Fazal, N, Fechner, K, Furkert, J, Krause, E, Roloff, B, Sayeed, M, Wei, E, Zbytek, B, Zipper, J, Wortsman, J, Paus, R. Cutaneous expression of CRH and CRH-R. Is there a "skin stress response system?". Ann N Y Acad Sci, 885, 287-311, 1999.
  89. Chakraborty, AK, Funasaka, Y, Slominski, A, Bolognia, J, Sodi, S, Ichihashi, M, Pawelek, JM. UV light and MSH receptors. Ann N Y Acad Sci, 885, 100-16, 1999.
  90. Carlson, JA, Healy, K, Slominski, A, Mihm, MC. Melanocytic matricoma: a report of two cases of a new entity. Am J Dermatopathol, 21 (4), 344-9, 1999.
  91. Slominski, A, Gomez-Sanchez, CE, Foecking, MF, Wortsman, J. Metabolism of progesterone to DOC, corticosterone and 18OHDOC in cultured human melanoma cells. FEBS Lett, 455 (3), 364-6, 1999.
  92. Slominski, A, Heasley, D, Mazurkiewicz, JE, Ermak, G, Baker, J, Carlson, JA. Expression of proopiomelanocortin (POMC)-derived melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH) peptides in skin of basal cell carcinoma patients. Hum Pathol, 30 (2), 208-15, 1999.
  93. Slominski, A, Wortsman, J, Nickoloff, B, McClatchey, K, Mihm, MC, Ross, JS. Molecular pathology of malignant melanoma. Am J Clin Pathol, 110 (6), 788-94, 1998.
  94. Slominski, A, Paus, R, Mihm, MC. Inhibition of melanogenesis as an adjuvant strategy in the treatment of melanotic melanomas: selective review and hypothesis. Anticancer Res, 18 (5B), 3709-15, 1998.
  95. Slominski, A, Botchkareva, NV, Botchkarev, VA, Chakraborty, A, Luger, T, Uenalan, M, Paus, R. Hair cycle-dependent production of ACTH in mouse skin. Biochim Biophys Acta, 1448 (1), 147-52, 1998.
  96. Fazal, N, Slominski, A, Choudhry, MA, Wei, ET, Sayeed, MM. Effect of CRF and related peptides on calcium signaling in human and rodent melanoma cells. FEBS Lett, 435 (2-3), 187-90, 1998.
  97. Slominski, A, Pawelek, J. Animals under the sun: effects of ultraviolet radiation on mammalian skin. Clin Dermatol, 16 (4), 503-15, 1998.
  98. Slominski, A, Ermak, G, Mazurkiewicz, JE, Baker, J, Wortsman, J. Characterization of corticotropin-releasing hormone (CRH) in human skin. J Clin Endocrinol Metab, 83 (3), 1020-4, 1998.
  99. Ermak, G, Slominski, A. Production of POMC, CRH-R1, MC1, and MC2 receptor mRNA and expression of tyrosinase gene in relation to hair cycle and dexamethasone treatment in the C57BL/6 mouse skin. J Invest Dermatol, 108 (2), 160-5, 1997.
  100. Slominski, A, Goodman-Snitkoff, G, Maurer, M, Paus, R. Hair cycle-associated changes in splenocyte proliferation. In Vivo, 11 (1), 101-2, 1997.
  101. Slominski, A, Baker, J, Ermak, G, Chakraborty, A, Pawelek, J. Ultraviolet B stimulates production of corticotropin releasing factor (CRF) by human melanocytes. FEBS Lett, 399 (1-2), 175-6, 1996.
  102. Slominski, A, Mihm, MC. Potential mechanism of skin response to stress. Int J Dermatol, 35 (12), 849-51, 1996.
  103. Chakraborty, AK, Funasaka, Y, Slominski, A, Ermak, G, Hwang, J, Pawelek, JM, Ichihashi, M. Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B. Biochim Biophys Acta, 1313 (2), 130-8, 1996.
  104. Slominski, A, Ermak, G, Mihm, M. ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin. J Clin Endocrinol Metab, 81 (7), 2746-9, 1996.
  105. Slominski, A, Paus, R, Plonka, P, Handjiski, B, Maurer, M, Chakraborty, A, Mihm, MC. Pharmacological disruption of hair follicle pigmentation by cyclophosphamide as a model for studying the melanocyte response to and recovery from cytotoxic drug damage in situ. J Invest Dermatol, 106 (6), 1203-11, 1996.
  106. Slominski, A, Baker, J, Rosano, TG, Guisti, LW, Ermak, G, Grande, M, Gaudet, SJ. Metabolism of serotonin to N-acetylserotonin, melatonin, and 5-methoxytryptamine in hamster skin culture. J Biol Chem, 271 (21), 12281-6, 1996.
  107. Slominski, A, Ermak, G, Hwang, J, Mazurkiewicz, J, Corliss, D, Eastman, A. The expression of proopiomelanocortin (POMC) and of corticotropin releasing hormone receptor (CRH-R) genes in mouse skin. Biochim Biophys Acta, 1289 (2), 247-51, 1996.
  108. Chakraborty, A, Slominski, A, Ermak, G, Hwang, J, Pawelek, J. Ultraviolet B and melanocyte-stimulating hormone (MSH) stimulate mRNA production for alpha MSH receptors and proopiomelanocortin-derived peptides in mouse melanoma cells and transformed keratinocytes. J Invest Dermatol, 105 (5), 655-9, 1995.
  109. Slominski, A, Ermak, G, Hwang, J, Chakraborty, A, Mazurkiewicz, JE, Mihm, M. Proopiomelanocortin, corticotropin releasing hormone and corticotropin releasing hormone receptor genes are expressed in human skin. FEBS Lett, 374 (1), 113-6, 1995.
  110. Chhieng, DC, Jennings, TA, Slominski, A, Mihm, MC. Choriocarcinoma presenting as a cutaneous metastasis. J Cutan Pathol, 22 (4), 374-7, 1995.
  111. Slominski, A, Ross, J, Mihm, MC. Cutaneous melanoma: pathology, relevant prognostic indicators and progression. Br Med Bull, 51 (3), 548-69, 1995.
  112. Slominski, A, Paus, R, Plonka, P, Chakraborty, A, Maurer, M, Pruski, D, Lukiewicz, S. Melanogenesis during the anagen-catagen-telogen transformation of the murine hair cycle. J Invest Dermatol, 102 (6), 862-9, 1994.
  113. Slominski, A, Paus, R. Towards defining receptors for L-tyrosine and L-dopa. Mol Cell Endocrinol, 99 (2), C7-11, 1994.
  114. Slominski, A, Chassalevris, N, Mazurkiewicz, J, Maurer, M, Paus, R. Murine skin as a target for melatonin bioregulation. Exp Dermatol, 3 (1), 45-50, 1994.
  115. Slominski, A, Wortsman, J, Mazurkiewicz, JE, Matsuoka, L, Dietrich, J, Lawrence, K, Gorbani, A, Paus, R. Detection of proopiomelanocortin-derived antigens in normal and pathologic human skin. J Lab Clin Med, 122 (6), 658-66, 1993.
  116. Slominski, A, Paus, R, Schadendorf, D. Melanocytes as "sensory" and regulatory cells in the epidermis. J Theor Biol, 164 (1), 103-20, 1993.
  117. Slominski, A, Paus, R. Melanogenesis is coupled to murine anagen: toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth. J Invest Dermatol, 101 (1 Suppl), 90S-97S, 1993.
  118. Slominski, A, Pruski, D. Melatonin inhibits proliferation and melanogenesis in rodent melanoma cells. Exp Cell Res, 206 (2), 189-94, 1993.
  119. Slominski, A, Paus, R, Wortsman, J. On the potential role of proopiomelanocortin in skin physiology and pathology. Mol Cell Endocrinol, 93 (1), C1-6, 1993.
  120. Slominski, A, Friedrich, T. L-dopa inhibits in vitro phosphorylation of melanoma glycoproteins. Pigment Cell Res, 5 (6), 396-9, 1992.
  121. Slominski, A, McNeely, T, Pawelek, J. Defect of insulin receptor in insulin-resistant variants of Cloudman S91 mouse melanoma cells. Melanoma Res, 2 (2), 115-22, 1992.
  122. Slominski, A, Goodman-Snitkoff, GG. Dopa inhibits induced proliferative activity of murine and human lymphocytes. Anticancer Res, 12 (3), 753-6, 1992.
  123. Slominski, A, Costantino, R, Wortsman, J, Paus, R, Ling, N. Melanotropic activity of gamma MSH peptides in melanoma cells. Life Sci, 50 (15), 1103-8, 1992.
  124. Slominski, A, Paus, R, Mazurkiewicz, J. Proopiomelanocortin expression in the skin during induced hair growth in mice. Experientia, 48 (1), 50-4, 1992.
  125. Slominski, A, Paus, R, Mazurkiewicz, J. Pro-opiomelanocortin expression and potential function of pro-opiomelanocortin products during induced hair growth in mice. Ann N Y Acad Sci, 642, 459-61, 1991.
  126. Slominski, A. POMC gene expression in mouse and hamster melanoma cells. FEBS Lett, 291 (2), 165-8, 1991.
  127. Slominski, A. L-tyrosine-binding proteins on melanoma cells. In Vitro Cell Dev Biol, 27A (9), 735-8, 1991.
  128. Slominski, A, Costantino, R. L-tyrosine induces tyrosinase expression via a posttranscriptional mechanism. Experientia, 47 (7), 721-4, 1991.
  129. Slominski, A, Paus, R, Costantino, R. Differential expression and activity of melanogenesis-related proteins during induced hair growth in mice. J Invest Dermatol, 96 (2), 172-9, 1991.
  130. Slominski, A, Costantino, R. Molecular mechanism of tyrosinase regulation by L-dopa in hamster melanoma cells. Life Sci, 48 (21), 2075-9, 1991.
  131. Howe, J, Costantino, R, Slominski, A. On the putative mechanism of induction and regulation of melanogenesis by L-tyrosine. Acta Derm Venereol, 71 (2), 150-2, 1991.
  132. Slominski, A, Costantino, R, Howe, J, Moellmann, G. Molecular mechanisms governing melanogenesis in hamster melanomas: relative abundance of tyrosinase and catalase-B (gp 75). Anticancer Res, 11 (1), 257-62, 1991.
  133. Slominski, A, Paus, R. Are L-tyrosine and L-dopa hormone-like bioregulators. J Theor Biol, 143 (1), 123-38, 1990.
  134. Slominski, A, Jastreboff, P, Pawelek, J. L-tyrosine stimulates induction of tyrosinase activity by MSH and reduces cooperative interactions between MSH receptors in hamster melanoma cells. Biosci Rep, 9 (5), 579-86, 1989.
  135. Slominski, A, Paus, R, Bomirski, A. Hypothesis: possible role for the melatonin receptor in vitiligo: discussion paper. J R Soc Med, 82 (9), 539-41, 1989.
  136. Slominski, A, Moellmann, G, Kuklinska, E. MSH inhibits growth in a line of amelanotic hamster melanoma cells and induces increases in cyclic AMP levels and tyrosinase activity without inducing melanogenesis. J Cell Sci, 92 ( Pt 4), 551-9, 1989.
  137. Slominski, A, Moellmann, G, Kuklinska, E. L-tyrosine, L-dopa, and tyrosinase as positive regulators of the subcellular apparatus of melanogenesis in Bomirski Ab amelanotic melanoma cells. Pigment Cell Res, 2 (2), 109-16, 1989.
  138. Slominski, A. L-tyrosine induces synthesis of melanogenesis related proteins. Life Sci, 45 (19), 1799-803, 1989.
  139. Bomirski, A, Słominski, A, Bigda, J. The natural history of a family of transplantable melanomas in hamsters. Cancer Metastasis Rev, 7 (2), 95-118, 1988.
  140. Słominski, A, Moellmann, G, Kuklinska, E, Bomirski, A, Pawelek, J. Positive regulation of melanin pigmentation by two key substrates of the melanogenic pathway, L-tyrosine and L-dopa. J Cell Sci, 89 ( Pt 3), 287-96, 1988.
  141. Pawelek, J, Bolognia, J, McLane, J, Murray, M, Osber, M, Słominski, A. A possible role for melanin precursors in regulating both pigmentation and proliferation of melanocytes. Prog Clin Biol Res, 256, 143-54, 1988.
  142. Slominski, A, Pawelek, J. MSH binding in Bomirski amelanotic hamster melanoma cells is stimulated by L-tyrosine. Biosci Rep, 7 (12), 949-54, 1987.